FAST GAS CHROMATOGRAPH METHOD AND DEVICE FOR ANALYZING A SAMPLE
First Claim
1. A method for fast gas chromatography analysis, said method comprising:
- injecting a sample to be analyzed into a gas chromatograph injector that is coupled to a gas chromatography capillary column;
transferring said sample in said injector into said capillary column with a carrier gas flow;
transferring said capillary column through a gas chromatograph oven as a flexible non-rigid capillary into a resistively heated metal tube having opposing input and output ends;
locating the input and output ends of said resistively heated metal tube near a hole in the gas chromatograph oven body so that a substantial portion of said column in said heated metal tube is located outside said gas chromatograph oven and so that said input and output ends project a short distance inside said gas chromatograph oven;
introducing an end of said portion of said capillary column that is outside the gas chromatograph oven from said heated metal tube into said gas chromatograph oven as a flexible capillary;
connecting said flexible capillary with a transfer line that leads into a gas chromatograph detector;
connecting both ends of said resistively heated metal tube to a power supply; and
resistively heating said heated metal tube in a time programmed manner to facilitate fast temperature program of said capillary column;
wherein said capillary column is flexibly connected to said gas chromatograph injector and detector.
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Accused Products
Abstract
In a fast gas chromatograph (GC) method and device for obtaining fast gas chromatography analysis, a capillary gas chromatography column is inserted into a resistively heated metal tube located mostly outside a standard gas chromatograph oven, which may serve as a heated transfer line to a flexible column that enters the resistively heated metal tube from its injector and exits into its detector. The fast GC device enables less than one minute full range temperature programming and cooling back analysis cycle time. The fast GC according to one embodiment is combined with mass spectrometry with supersonic molecular beams for the provision of fast analysis cycle time together with highly informative mass spectral information for improved sample analysis and identification.
22 Citations
36 Claims
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1. A method for fast gas chromatography analysis, said method comprising:
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injecting a sample to be analyzed into a gas chromatograph injector that is coupled to a gas chromatography capillary column; transferring said sample in said injector into said capillary column with a carrier gas flow; transferring said capillary column through a gas chromatograph oven as a flexible non-rigid capillary into a resistively heated metal tube having opposing input and output ends; locating the input and output ends of said resistively heated metal tube near a hole in the gas chromatograph oven body so that a substantial portion of said column in said heated metal tube is located outside said gas chromatograph oven and so that said input and output ends project a short distance inside said gas chromatograph oven; introducing an end of said portion of said capillary column that is outside the gas chromatograph oven from said heated metal tube into said gas chromatograph oven as a flexible capillary; connecting said flexible capillary with a transfer line that leads into a gas chromatograph detector; connecting both ends of said resistively heated metal tube to a power supply; and resistively heating said heated metal tube in a time programmed manner to facilitate fast temperature program of said capillary column; wherein said capillary column is flexibly connected to said gas chromatograph injector and detector. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18)
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19. A fast gas chromatograph device for obtaining fast gas chromatography analysis, said device comprising:
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a gas chromatograph injector; a capillary gas chromatography column; a connector for connecting said capillary column with said gas chromatograph injector; a source of carrier gas flow for the transferring of sample vapor in said injector into said capillary column; a metal tube that is adapted to be resistively heated and that is located mostly outside a gas chromatograph oven and that is coupled via a flexible capillary column to said gas chromatograph injector and detector; a transfer line with a connector for connecting said flexible capillary column to a gas chromatograph detector; said input and output ends of said metal tube being located near a hole in the gas chromatograph oven body so that a substantial portion of said column in said metal tube is located outside said gas chromatograph oven; means for coupling a power supply to both ends of said metal tube for its resistive heating; and a controller configured for resistively heating said metal tube in a time programmed manner to facilitate fast temperature program of said capillary column in said heated metal tube. - View Dependent Claims (20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36)
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Specification