Calibration of Analyte Measurement System

• US 20120108931A1
• Filed: 06/29/2011
• Published: 05/03/2012
• Est. Priority Date: 06/29/2010
• Status: Active Grant

• Current Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories Incorporated)
• Inventors: Taub, Marc Barry, Harper, Wesley Scott, Berman, Glenn Howard, Huang, Jean Mei
• Granted Patent: US 10,092,229 B2
• Time in Patent Office: Days
• US Class Current: 600/347
• CPC Class Codes: A61B 2560/0252 using ambient temperature
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/1468 using chemical or electrochemical methods, e.g. by polarographic means A61B5/1486 takes precedence
• CPC Class Codes: A61B 5/1495 Calibrating or testing of in-vivo probes
• CPC Class Codes: G16H 20/00 ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
• CPC Class Codes: G16H 20/10 relating to drugs or medications, e.g. for ensuring correct administration to patients
• CPC Class Codes: G16H 40/40 for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades

Abstract

A method of calibrating an analyte measurement system is provided.

Claims

1. A method, comprising:

generating a signal from the sensor, the signal corresponding to an analyte concentration level in a biofluid of a subject;

prompting a user to assay a calibration sample of the user'"'"'s blood to obtain a calibration value, if a first condition is met;

selecting a first time frame and a maximum number of calibration in the first time frame; and

correlating the calibration value to at least one of the signals from the sensor if the first condition of is met;

wherein the first condition is met if fewer than the maximum number of calibrations have occurred in the first time frame.

2. The method of claim 1, further comprising selecting a second time frame.

3. The method of claim 2, further comprising selecting a maximum number of calibrations in the second time frame.

4. The method of claim 3, wherein the first condition is met if fewer than the maximum number of calibrations have occurred in the second time frame.

5. The method of claim 1, further comprising prompting the user to assay a calibration sample of the user'"'"'s blood to obtain a calibration value, if a second condition is met.

6. The method of claim 5, further comprising allowing the user to select a time period in which calibrations are not accepted.

7. The method of claim 6, wherein the second condition is met if the current time is outside the selected time period.

8. The method of claim 1, further comprising prompting the user to assay a calibration sample of the user'"'"'s blood to obtain a calibration value, if a third condition is met.

9. The method of claim 8, further comprising determining the presence of a condition relating the subject.

10. The method of claim 9, wherein the condition comprises a determination of whether the subject is asleep.

11. The method of claim 9, wherein the third condition is met if the condition does not exist.

12. The method of claim 1, wherein the analyte is glucose.

13. The method of claim 1, wherein obtaining the calibration value comprises determining the calibration measurement in less than or equal to about 1 μ

L of blood.

14. The method of claim 1, wherein the calibration value is compared to at least one signal from the sensor to calibrate the sensor.

15. A method, comprising:

generating a signal from the sensor, the signal corresponding to an analyte concentration level in a biofluid of a subject;

providing a user the option to select a time for obtaining a calibration sample of the user'"'"'s blood to obtain a calibration value; and

correlating the calibration value to at least one of the signals from the sensor if the current time corresponds to the selected time.

16. The method of claim 15, wherein providing a user an option to select a time comprises providing a user the option to select a date and a time for calibration.

17. The method of claim 15, wherein providing a user an option to select a time comprises providing a user the option to select a time for recurrent daily calibration.

18. An apparatus, comprising:

a processing unit; and

a memory coupled to the processing unit, the memory storing instructions which, when executed by the processing unit, causes the processing unit to receive a signal from a sensor, the signal corresponding to an analyte concentration level in a biofluid of a subject, prompt a user to assay a calibration sample of the user'"'"'s blood to obtain a calibration value, if a first condition is met, select a first time frame and a maximum number of calibration in the first time frame, and correlate the calibration value to at least one of the signals from the sensor if the first condition of is met, wherein the first condition is met if fewer than the maximum number of calibrations have occurred in the first time frame.

19. The apparatus of claim 18, wherein the memory further includes instructions which, when executed by the processing unit, causes the processing unit to select a second time frame.

20. The apparatus of claim 19, wherein the memory further includes instructions which, when executed by the processing unit, causes the processing unit to select a maximum number of calibrations in the second time frame.

21. The apparatus of claim 20, wherein the first condition is met if fewer than the maximum number of calibrations have occurred in the second time frame.

22. The apparatus of claim 18, wherein the memory further includes instructions which, when executed by the processing unit, causes the processing unit to prompt the user to assay a calibration sample of the user'"'"'s blood to obtain a calibration value, if a second condition is met.

23. The apparatus of claim 22, wherein the memory further includes instructions which, when executed by the processing unit, causes the processing unit to allow the user to select a time period in which calibrations are not accepted.

24. The apparatus of claim 23, wherein the second condition is met if the current time is outside the selected time period.

25. The apparatus of claim 18, wherein the memory further includes instructions which, when executed by the processing unit, causes the processing unit to prompt the user to assay a calibration sample of the user'"'"'s blood to obtain a calibration value, if a third condition is met.

26. The apparatus of claim 25, wherein the memory further includes instructions which, when executed by the processing unit, causes the processing unit to determine the presence of a condition relating the subject.

27. The apparatus of claim 26, wherein the condition comprises a determination of whether the subject is asleep.

28. The apparatus of claim 26, wherein the third condition is met if the condition does not exist.

29. The apparatus of claim 18, wherein the analyte is glucose.

30. The apparatus of claim 18, wherein instructions to obtain the calibration value comprises instructions to determine the calibration measurement in less than or equal to about 1 μ

L of blood.

31. The apparatus of claim 18, wherein the calibration value is compared to at least one signal from the sensor to calibrate the sensor.

32. An apparatus, comprising:

a processing unit; and

a memory storing instructions which, when executed by the processing unit, causes the processing unit to generate a signal from a sensor, the signal corresponding to an analyte concentration level in a biofluid of a subject, provide a user the option to select a time for obtaining a calibration sample of the user'"'"'s blood to obtain a calibration value, and correlate the calibration value to at least one of the signals from the sensor if the current time corresponds to the selected time.

33. The apparatus of claim 32, wherein the instructions to provide a user an option to select a time comprises instructions to provide a user the option to select a date and a time for calibration.

34. The apparatus of claim 32, wherein the instructions to provide a user an option to select a time comprises instructions to provide a user the option to select a time for recurrent daily calibration.