Parallel Preparation of High Fidelity Probes in an Array Format
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Abstract
The present invention provides massively parallel oligonucleotide synthesis and purification for applications that utilize large collections of defined high-fidelity oligonucleotides (e.g., from about 101 to about 105 different sequences, generally between 25-160 bases in length).
1 Citation
50 Claims
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1-38. -38. (canceled)
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39. A method of synthesizing one or more oligonucleotides on a solid substrate, wherein the method comprises:
attaching to a solid substrate one or more ribonucleotides having the following structure; - View Dependent Claims (40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50)
Specification