TISSUE THICKNESS COMPENSATOR COMPRISING CONTROLLED RELEASE AND EXPANSION
First Claim
1. A tissue thickness compensator comprising:
- a first layer comprising a first biocompatible material sealingly enclosed in a water impermeable material; and
a second layer comprising a second biocompatible material comprising at least one encapsulation;
wherein the first biocompatible material expands when contacted with a fluid.
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Accused Products
Abstract
A tissue thickness compensator may generally comprise a first layer comprising a first biocompatible material sealingly enclosed in a water impermeable material and a second layer comprising a second biocompatible material comprising at least one encapsulation, wherein the first biocompatible material expands when contacted with a fluid. The tissue thickness compensator may comprise a haemostatic agent, an anti-inflammatory agent, an antibiotic agent, anti-microbial agent, an anti-adhesion agent, an anti-coagulant agent, a medicament, and/or pharmaceutically active agent. The encapsulation may comprise a biodegradable material to degrade in vivo and/or in situ. The tissue thickness compensator may comprise a hydrogel. The reaction product may comprise a fluid-swellable composition. Articles of manufacture comprising the tissue thickness compensator and methods of making and using the tissue thickness compensator are also described.
941 Citations
19 Claims
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1. A tissue thickness compensator comprising:
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a first layer comprising a first biocompatible material sealingly enclosed in a water impermeable material; and a second layer comprising a second biocompatible material comprising at least one encapsulation; wherein the first biocompatible material expands when contacted with a fluid. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
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16. A tissue thickness compensator comprising:
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an inner layer comprising a hydrogel impregnated with at least one of a haemostatic agent, an anti-inflammatory agent, an antibiotic agent, anti-microbial agent, an anti-adhesion agent, an anti-coagulant agent, a medicament, and a pharmaceutically active agent; and an outer layer comprising a water impermeable material sealingly enclosing the inner layer; wherein the hydrogel expands when contacted with at least one of water, saline, and a bodily fluid. - View Dependent Claims (17)
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18. A method of making a tissue thickness compensator, the method comprising:
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providing a tissue thickness compensator comprising; an inner layer comprising a biocompatible material; and an outer layer comprising a water impermeable material sealingly enclosing the inner layer; and impregnating the inner layer with at least one of a haemostatic agent, an anti-inflammatory agent, an antibiotic agent, anti-microbial agent, an anti-adhesion agent, an anti-coagulant agent, a medicament, and a pharmaceutically active agent; wherein the biocompatible material expands when contacted with at least one of water, saline, and a bodily fluid. - View Dependent Claims (19)
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Specification