SILOXANE MONOMERS CONTAINING HYDROLYSIS RESISTANCE CARBOSILOXANE LINKAGE, PROCESS FOR THEIR PREPARATION AND THIN FILMS CONTAINING THE SAME FOR CONTACT LENS APPLICATION
First Claim
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1. A silicone monomer comprising of at least one carbosiloxane linkage having the general formulae (I):
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(R1R2R3)Si—
Y1—
[Si(R4R5)(Y2)]a—
Si(R6R7)—
Z
(I)wherein a is 0 to about 100;
Y1 is a substituted or unsubstituted divalent alkyl linking group of 1 to about 10 carbon atoms;
Y2 is a substituted or unsubstituted divalent alkyl linking group of 1 to about 10 carbon atoms or a hetero atom;
R1, R2, R3, R4, R5, R6, and R7 is independently selected from the group consisting of monovalent aliphatic, cycloaliphatic or aromatic or halogenated hydrocarbon groups of 1 to about 10 carbons, —
Y2—
Si(R8R9R10) and/or A, wherein R8R9R10 is independently selected from the group consisting of monovalent aliphatic, cycloaliphatic and aromatic hydrocarbon groups of 1 to about 10 carbons;
A is a monovalent hydrophilic or hydrophobic moiety selected from the group consisting of substituted or unsubstituted, saturated and unsaturated aliphatic, cycloaliphatic or aromatic hydrocarbons and substituted or unsubstituted, saturated and unsaturated aliphatic, cycloaliphatic or aromatic hydrocarbons containing hetero atoms;
Z has the following general formulae (II)
—
R11—
B—
X
(II)wherein R11 is a linear or branched, divalent alkyl linking group having 0 to about 20 carbon atoms, B is a divalent hydrophilic or hydrophobic moiety selected from the group consisting of substituted or unsubstituted, saturated and unsaturated aliphatic, cycloaliphatic or aromatic hydrocarbons and substituted or unsubstituted, saturated and unsaturated aliphatic, cycloaliphatic or aromatic hydrocarbons containing hetero atoms and X is acrylamide or a polymerizable group selected from the group consisting of substituted or unsubstituted unsaturated aliphatic or aromatic hydrocarbons, acrylates and methacrylates.
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Abstract
There is provided new mono-(meth)acrylate functionalized silicone monomers containing carbosiloxane linkage for improved hydrolysis resistance, useful in making water absorbing silicone-hydrogel films for contact lens applications. This invention also provides homo-polymers and copolymers made from the mono-(meth)acrylate functionalized hydrophilic silicone monomers described herein. Also provided is a process for producing the monomers and polymers described herein and contact lenses produced from the same.
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Citations
38 Claims
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1. A silicone monomer comprising of at least one carbosiloxane linkage having the general formulae (I):
-
(R1R2R3)Si—
Y1—
[Si(R4R5)(Y2)]a—
Si(R6R7)—
Z
(I)wherein a is 0 to about 100; Y1 is a substituted or unsubstituted divalent alkyl linking group of 1 to about 10 carbon atoms; Y2 is a substituted or unsubstituted divalent alkyl linking group of 1 to about 10 carbon atoms or a hetero atom; R1, R2, R3, R4, R5, R6, and R7 is independently selected from the group consisting of monovalent aliphatic, cycloaliphatic or aromatic or halogenated hydrocarbon groups of 1 to about 10 carbons, —
Y2—
Si(R8R9R10) and/or A, wherein R8R9R10 is independently selected from the group consisting of monovalent aliphatic, cycloaliphatic and aromatic hydrocarbon groups of 1 to about 10 carbons;
A is a monovalent hydrophilic or hydrophobic moiety selected from the group consisting of substituted or unsubstituted, saturated and unsaturated aliphatic, cycloaliphatic or aromatic hydrocarbons and substituted or unsubstituted, saturated and unsaturated aliphatic, cycloaliphatic or aromatic hydrocarbons containing hetero atoms;Z has the following general formulae (II)
—
R11—
B—
X
(II)wherein R11 is a linear or branched, divalent alkyl linking group having 0 to about 20 carbon atoms, B is a divalent hydrophilic or hydrophobic moiety selected from the group consisting of substituted or unsubstituted, saturated and unsaturated aliphatic, cycloaliphatic or aromatic hydrocarbons and substituted or unsubstituted, saturated and unsaturated aliphatic, cycloaliphatic or aromatic hydrocarbons containing hetero atoms and X is acrylamide or a polymerizable group selected from the group consisting of substituted or unsubstituted unsaturated aliphatic or aromatic hydrocarbons, acrylates and methacrylates. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38)
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Specification