SYSTEMS AND METHODS FOR PROCESSING SENSOR DATA

• US 20120259191A1
• Filed: 05/16/2012
• Published: 10/11/2012
• Est. Priority Date: 12/17/2007
• Status: Active Grant

• Current Assignee: DexCom Incorporated
• Original Assignee: DexCom Incorporated
• Inventors: Shariati, Mohammad Ali, Kamath, Apurv Ullas, Dobbles, J. Michael, Mahalingam, Aarthi
• Granted Patent: US 10,827,980 B2
• Time in Patent Office: Days
• US Class Current: 600/365
• CPC Class Codes: A61B 2560/0223 of calibration, e.g. protocols for calibrating sensors
• CPC Class Codes: A61B 2560/04 Constructional details of apparatus
• CPC Class Codes: A61B 2562/085 combined with means for recording calibration data
• CPC Class Codes: A61B 5/0008 Temperature signals
• CPC Class Codes: A61B 5/0031 Implanted circuitry
• CPC Class Codes: A61B 5/01 Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue clinical contact thermometers G01K13/20
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/14542 for measuring blood gases A61B5/14551 takes precedence
• CPC Class Codes: A61B 5/14546 for measuring analytes not otherwise provided for, e.g. ions, cytochromes
• CPC Class Codes: A61B 5/14865 invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
• CPC Class Codes: A61B 5/1495 Calibrating or testing of in-vivo probes
• CPC Class Codes: A61B 5/4839 combined with drug delivery
• CPC Class Codes: A61B 5/6848 Needles
• CPC Class Codes: A61B 5/7203 for noise prevention, reduction or removal
• CPC Class Codes: A61B 5/7221 Determining signal validity, reliability or quality A61B5/7207 and A61B5/7217 take precedence
• CPC Class Codes: A61B 5/7264 Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems neural networks per se G06N3/00; expert systems per se G06N5/00
• CPC Class Codes: A61B 5/742 using visual displays A61B5/339 takes precedence
• CPC Class Codes: A61B 5/743 Displaying an image simultaneously with additional graphical information, e.g. symbols, charts, function plots
• CPC Class Codes: A61B 5/7475 User input or interface means, e.g. keyboard, pointing device, joystick
• CPC Class Codes: A61M 5/1723 using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00
• CPC Class Codes: G16H 15/00 : ICT specially adapted for medical reports, e.g. generation or transmission thereof
• CPC Class Codes: G16H 20/00 : ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
• CPC Class Codes: G16H 20/10 : relating to drugs or medications, e.g. for ensuring correct administration to patients
• CPC Class Codes: G16H 20/17 : delivered via infusion or injection
• CPC Class Codes: G16H 40/40 : for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
• CPC Class Codes: G16H 40/63 : for local operation
• CPC Class Codes: G16H 50/50 : for simulation or modelling of medical disorders
• CPC Class Codes: Y02A 90/10 : Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Abstract

Systems and methods for processing sensor data are provided. In some embodiments, systems and methods are provided for calibration of a continuous analyte sensor. In some embodiments, systems and methods are provided for classification of a level of noise on a sensor signal. In some embodiments, systems and methods are provided for determining a rate of change for analyte concentration based on a continuous sensor signal. In some embodiments, systems and methods for alerting or alarming a patient based on prediction of glucose concentration are provided.

Claims

1. A method for classifying a level of noise in a signal obtained from a continuous glucose sensor based on a signal strength, the method comprising:

receiving a signal from a continuous glucose sensor during a sensor session;

classifying a level of noise in the signal during the sensor session based on one or more noise thresholds, wherein the one or more noise thresholds are adaptively determined during the sensor session; and

controlling an output responsive to the noise classification.

2. The method of claim 1, further comprising determining a signal strength of the signal from the continuous glucose sensor during the sensor session.

3. The method of claim 2, wherein the determining a signal strength comprises applying a low pass filter to the signal to determine the signal strength of the signal.

4. The method of claim 2, wherein the classifying comprises adaptively determining the one or more noise thresholds for classification of the level of noise in the signal, wherein the one or more noise thresholds are based the signal strength of the signal.

5. The method of claim 2, wherein the one or more noise thresholds are based on a percentage of the signal strength.

6. The method of claim 1, wherein the classifying comprises applying one or more low pass filters to a noise signal to obtain one or more noise indicators and comparing the one or more noise indicators with the one or more noise thresholds.

7. The method of claim 1, further comprising determining a noise signal from the sensor signal, wherein the classifying comprises applying one or more filters to the noise signal to obtain one or more noise indicators and comparing the one or more noise indicators with one or more noise thresholds.

8. The method of claim 1, wherein the controlling comprises outputting information indicative of the noise classification to an external device.

9. The method of claim 1, wherein the controlling comprises displaying information indicative of the noise classification on a user interface.

10. The method of claim 1, wherein the controlling comprises decision making for at least one of displaying, calibrating, alarming, sensor diagnostics or insulin delivery.

11. The method of claim 1, wherein the controlling comprises controlling a display of rate of change information.

12. The method of claim 1, wherein the controlling comprises controlling an alarm indicative of at least one of hypoglycemia, hyperglycemia, predicted hypoglycemia, or predicted hyperglycemia.

13. The method of claim 1, wherein the controlling comprises controlling medicament therapy instructions.

14. A system for classifying a level of noise in a signal obtained from a continuous glucose sensor, the system comprising:

a continuous glucose sensor configured to provide a signal indicative of a glucose concentration in a host; and

a computer system configured to receive the signal from the continuous glucose sensor during a sensor session, to classify a level of noise in the signal during the sensor session based on one or more noise thresholds, and to control an output responsive to the noise classification, wherein the one or more noise thresholds are adaptively determined during the sensor session.

15. The system of claim 14, wherein the computer system is configured to determine a signal strength of the signal from the continuous glucose sensor during the sensor session.

16. The system of claim 15, wherein the computer system is configured to determine a signal strength by applying a low pass filter to the signal.

17. The system of claim 15, wherein the computer system is configured to adaptively determine the one or more noise thresholds for classification of the level of noise in the signal based on the signal strength of the signal.

18. The system of claim 15, wherein the computer system is configured to adaptively determine the one or more noise thresholds for classification of the level of noise on the signal based on a percentage of the signal strength.

19. The system of claim 14, wherein the computer system is configured to apply one or more low pass filters to a noise signal to obtain one or more noise indicators and to compare the one or more noise indicators with the one or more noise thresholds.

20. The system of claim 14, wherein the computer system is configured to determine a noise signal from the sensor signal by applying one or more filters to the noise signal to obtain one or more noise indicators and comparing the one or more noise indicators with one or more noise thresholds.

21. The system of claim 14, wherein the output comprises information indicative of the noise classification.

22. The system of claim 14, wherein the computer system comprises a user interface, and wherein the output is displayed via the user interface.

23. The system of claim 14, wherein the computer system is configured to control the output by making decisions for at least one of displaying, calibrating, alarming, sensor diagnostics or insulin delivery.

24. The system of claim 14, wherein the computer system is configured to control an output by controlling a display of rate of change information.

25. The system of claim 14, wherein the computer system is configured to control an output by controlling an alarm indicative of at least one of hypoglycemia, hyperglycemia, predicted hypoglycemia, or predicted hyperglycemia.

26. The system of claim 14, wherein the computer system is configured to control an output by controlling control medicament therapy instructions.