ELECTRICAL BRAIN THERAPY PARAMETER DETERMINATION BASED ON A BIOELECTRICAL RESONANCE RESPONSE
First Claim
1. A method for configuring therapy, comprising:
- delivering electrical stimulation to a brain at a plurality of different stimulation frequencies;
sensing one or more bioelectrical signals;
identifying a bioelectrical resonance response of the brain to the electrical stimulation, the bioelectrical resonance response identified based on a parameter of oscillation of the one or more bioelectrical signals and indicative of resonance of an area of the brain to one stimulation frequency of the plurality of stimulation frequencies;
setting a stimulation frequency parameter for a therapy based on the identified bioelectrical resonance response, wherein the stimulation frequency parameter is set at or near the one stimulation frequency; and
delivering the therapy to the brain using the set stimulation frequency parameter, wherein each of delivering electrical stimulation, sensing, identifying, setting, and delivering the therapy are performed at least in part by control circuitry.
1 Assignment
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Accused Products
Abstract
Various methods and apparatuses are disclosed that concern delivering electrical stimulation to a brain at a plurality of different stimulation frequencies, sensing one or more bioelectrical signals, and identifying a bioelectrical resonance response of the brain to the electrical stimulation. The bioelectrical resonance response may be identified based on a parameter of oscillation of the one or more bioelectrical signals and indicative of resonance of an area of the brain to one stimulation frequency of the plurality of stimulation frequencies. A stimulation frequency parameter for a therapy may be set based on the identified bioelectrical resonance response, wherein the stimulation frequency parameter is set at or near the one stimulation frequency.
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Citations
26 Claims
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1. A method for configuring therapy, comprising:
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delivering electrical stimulation to a brain at a plurality of different stimulation frequencies; sensing one or more bioelectrical signals; identifying a bioelectrical resonance response of the brain to the electrical stimulation, the bioelectrical resonance response identified based on a parameter of oscillation of the one or more bioelectrical signals and indicative of resonance of an area of the brain to one stimulation frequency of the plurality of stimulation frequencies; setting a stimulation frequency parameter for a therapy based on the identified bioelectrical resonance response, wherein the stimulation frequency parameter is set at or near the one stimulation frequency; and delivering the therapy to the brain using the set stimulation frequency parameter, wherein each of delivering electrical stimulation, sensing, identifying, setting, and delivering the therapy are performed at least in part by control circuitry. - View Dependent Claims (3, 4, 6, 7, 8, 9, 11, 12, 13)
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2. The method of claim I, wherein delivering the electrical stimulation comprises delivering the electrical stimulation for each of a plurality of stimulation intervals, the electrical stimulation being delivered for each stimulation interval of the plurality at a respective stimulation frequency of the plurality of different stimulation frequencies.
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5. The method of claim I, wherein the electrical stimulation is delivered to the subthalamic nucleus, and the area of the brain for which the bioelectrical resonance response is identified is the subthalamic nucleus.
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10. The method of claim I, wherein delivering electrical stimulation to the brain at the plurality of different stimulation frequencies comprises delivering electrical stimulation to the brain at the plurality of different stimulation frequencies for each of a plurality of different stimulation amplitude values, and wherein the method further comprises setting a stimulation amplitude parameter of the therapy, the amplitude parameter being set at or slightly higher than the lowest amplitude value of the plurality of different stimulation amplitude values for which the bioelectrical resonance response was identified.
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14. A system comprising:
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one or more sensors configured to receive one or more bioelectrical signals indicative of brain activity; a stimulation generator configured to deliver electrical stimulation to a brain; and control circuitry configured to; control the stimulation generator to deliver the electrical stimulation to a brain at a plurality of different stimulation frequencies; identify a bioelectrical resonance response of the brain to the electrical stimulation, the bioelectrical resonance response identified based on a parameter of oscillation of the one or more bioelectrical signals and indicative of resonance of an area of the brain to one stimulation frequency of the plurality of stimulation frequencies; set a stimulation frequency parameter for a therapy based on the identified bioelectrical resonance response, the stimulation frequency parameter set at or near the one stimulation frequency; and control the stimulation generator to deliver the therapy to the brain using the set stimulation frequency parameter. - View Dependent Claims (15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25)
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26. A system, comprising:
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means for delivering electrical stimulation to a brain at a plurality of different stimulation frequencies; means for sensing one or more bioelectrical signals; means for identifying a bioelectrical resonance response of the brain to the electrical stimulation, the bioelectrical resonance response identified based on a parameter of oscillation of the one or more bioelectrical signals and indicative of resonance of an area of the brain to one stimulation frequency of the plurality of stimulation frequencies; means for setting a stimulation frequency parameter for a therapy based on the identified bioelectrical resonance response, wherein the stimulation frequency parameter is set at or near the one stimulation frequency; and means for delivering the therapy to the brain using the set stimulation frequency parameter.
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Specification