Flow Directional Infusion Device

  • US 20130079731A1
  • Filed: 09/12/2012
  • Published: 03/28/2013
  • Est. Priority Date: 09/28/2011
  • Status: Active Grant
First Claim
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1. A flow directional infusion device for reducing reflux of an infusate in a vessel during a therapy procedure, comprises:

  • a) a catheter having a proximal portion and a distal portion with a distal end; and

    b) a composite filter valve located at said distal portion of said catheter, said filter valve having a proximal end fixed to said catheter, and a distal end, and a length extending between said proximal and distal ends,i) a plurality of elongate first polymeric filaments each having a diameter of 0.025 mm to 0.127 mm, said first filaments having a proximal end, a distal end, and a length extending therebetween,said proximal ends secured relative to each other, said first filaments along said lengths distal of said proximal ends not bonded to each other such that said first filaments are movable relative to each other and defining a valve,said valve fully collapsible into an undeployed state, and expandable from said undeployed state into a radially-expanded deployed state by a spring bias of said first filaments,wherein in said deployed state said first filaments cross one another at an angle of 100°

    to 150°

    , and said first filaments have a Young'"'"'s modulus of elasticity greater than 100 MPa, andii) a filter formed by second filaments that integrated are with valve by electrostatically depositing or spinning polymeric second filaments onto the braided first filaments, said filter defining a pore size not exceeding 500 μ

    m,wherein said filter valve expands from said undeployed state to said deployed state in less than one second in an at-rest fluid having a viscosity of 3.2 cP,said once said filter valve is in said deployed state, said filter valve dynamically movable within the vessel between an expanded valve-open configuration and a collapsed valve-closed configuration depending on the local biological fluid flow conditions about said filter valve, and when said filter valve is in said valve-open configuration said pore size of said filter renders said filter impermeable to the embolic agent of the infusate, andsaid filter valve having a circumferential wall defining an opening located proximal said distal end of said filter valve for transfer of the infusate from a location within said catheter through said opening to outside said filter valve.

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