METHOD AND SYSTEM FOR DETERMINING THE ACCURACY OF DNA BASE IDENTIFICATIONS
First Claim
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1. A method in a computer for determining the quality of predicted DNA base identifications, the method comprising:
- receiving a training data set, the training data set comprising a plurality of predicted DNA base identifications;
defining a group of subsets;
comparing the predicted DNA base identifications with actual DNA base identifications for training data within each subset of the group;
determining a sampling characteristic for each subset of the group based on training data within the respective subset; and
determining, with a processor, a quality characterization for predicted DNA base identifications within at least one of subset of the group based on the comparison and determined sampling characteristic;
wherein the sampling characteristic comprises a confidence value comprising a binomial proportion confidence interval value.
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Abstract
Embodiments disclosed herein relate to a method and system for determining the accuracy of DNA base identifications, based at least partly on sampling characteristics of subsets within training data sets.
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19 Claims
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1. A method in a computer for determining the quality of predicted DNA base identifications, the method comprising:
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receiving a training data set, the training data set comprising a plurality of predicted DNA base identifications; defining a group of subsets; comparing the predicted DNA base identifications with actual DNA base identifications for training data within each subset of the group; determining a sampling characteristic for each subset of the group based on training data within the respective subset; and determining, with a processor, a quality characterization for predicted DNA base identifications within at least one of subset of the group based on the comparison and determined sampling characteristic; wherein the sampling characteristic comprises a confidence value comprising a binomial proportion confidence interval value. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19)
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