CORPUS CALLOSUM NEUROMODULATION ASSEMBLY

• US 20130238068A1
• Filed: 04/05/2013
• Published: 09/12/2013
• Est. Priority Date: 05/04/2004
• Status: Active Grant

• Current Assignee: Cleveland Clinic Foundation
• Original Assignee: Cleveland Clinic Foundation
• Inventors: MACHADO, Andre, REZAI, Ali R.
• Granted Patent: US 8,942,812 B2
• Time in Patent Office: Days
• US Class Current: 607/116
• CPC Class Codes: A61N 1/0531 Brain cortex electrodes
• CPC Class Codes: A61N 1/0534 Electrodes for deep brain stimulation
• CPC Class Codes: A61N 1/0539 Anchoring of brain electrode systems, e.g. within burr hole
• CPC Class Codes: A61N 1/3605 Implantable neurostimulators for stimulating central or peripheral nerve system
• CPC Class Codes: A61N 1/36082 Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease

Abstract

Neuromodulation assemblies with lead bodies having curvatures that mimic the curvatures of the splenium, trunk, genu, or rostrum of the corpus callosum. Methods of stimulating the corpus callosum and methods of securing an electrical lead in the brain are also provided.

Claims

1. -22. (canceled)

23. A method of stimulating a corpus callosum, the method comprising:

placing an electrical lead having an electrode disposed thereon in communication with a corpus callosum; and

activating the electrode to apply an electrical signal to the corpus callosum to stimulate the corpus callosum.

24. The method of claim 23, wherein the electrode comprises a plurality of electrodes.

25. The method of claim 23, wherein the electrical lead penetrates the corpus callosum.

26. The method of claim 23, wherein the electrical lead is delivered to the corpus callosum intravascularly.

27. The method of claim 23, wherein the corpus callosum has an under-surface and the electrical lead is placed on the under-surface of the corpus callosum.

28. The method of claim 25, wherein the electrical lead is cylindrical.

29. A method of securing in the brain an electrical lead comprising a lead body having an electrode disposed thereon, the method comprising anchoring the electrical lead to the dura mater of the brain.

30. The method of claim 29, wherein the dura mater is the dura mater of the convexity.

31. The method of claim 29, wherein the dura mater is the falx.