ANCHORED NON-PIERCING DUODENAL SLEEVE AND DELIVERY SYSTEMS
First Claim
1. A transorally inserted, intragastric device for the treatment of obesity, comprising:
- a sleeve for placement in the duodenum having a tubular body with proximal and distal ends; and
a radially collapsible anchor surrounding the proximal end of the tubular body, the anchor having an expanded state that can act to prevent passage of the device through the pyloric sphincter, the anchor including two conical flanges concentrically-disposed around the tubular body and angled away from one another so as to impede movement of the anchor within the duodenum in both a proximal direction and in a distal direction,wherein the device is formed of a material that will resist structural degradation over a period of at least six months within the gastrointestinal tract.
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Accused Products
Abstract
An intragastric implant for obesity treatment is disclosed. The device delays digestion by providing a duodenal sleeve, and may also slows gastric emptying by limiting flow through the pyloric sphincter. The implant includes an elongated axially-compressible duodenal sleeve having a non-tissue-piercing anchor on a proximal end sized to lodge within the duodenal bulb. The anchor may have oppositely-directed anchoring flanges to resists migration in both directions. The sleeve may also have barbed ribs to resist proximal movement back up into the stomach. A method of implant includes collapsing/compressing the device and transorally advancing it through the esophagus to be deployed within the duodenum. A dissolvable jacket may constrain the implant for delivery and naturally dissolve upon implant. Removal of the implant may occur in the reverse.
28 Citations
21 Claims
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1. A transorally inserted, intragastric device for the treatment of obesity, comprising:
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a sleeve for placement in the duodenum having a tubular body with proximal and distal ends; and a radially collapsible anchor surrounding the proximal end of the tubular body, the anchor having an expanded state that can act to prevent passage of the device through the pyloric sphincter, the anchor including two conical flanges concentrically-disposed around the tubular body and angled away from one another so as to impede movement of the anchor within the duodenum in both a proximal direction and in a distal direction, wherein the device is formed of a material that will resist structural degradation over a period of at least six months within the gastrointestinal tract. - View Dependent Claims (2, 3, 4, 5)
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6. A transorally inserted, intragastric device for the treatment of obesity, comprising:
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a stomach anchoring member having a collapsed, delivery size, and an expanded, deployed size larger than a pyloric sphincter, the stomach anchoring member having no tissue-piercing elements; a duodenal anchoring member having a collapsed, delivery size, and an expanded, deployed size larger than a pyloric sphincter, the duodenal anchoring member having no tissue-piercing elements; an elongated duodenal sleeve for placement in the duodenum having a tubular body with proximal and distal ends, the proximal end extending to the stomach anchoring member on the stomach side of the pyloric sphincter, and forming a compressible channel through the pyloric sphincter; and a plurality of cords extending the length of the device from the stomach anchoring member to the distal end of the duodenal sleeve, wherein the device is formed of a material that will resist structural degradation over a period of at least six months within the gastrointestinal tract. - View Dependent Claims (7, 8, 9, 10, 11, 12, 13)
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14. A transorally inserted, intragastric device for the treatment of obesity, comprising:
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a stomach anchoring member comprising at least one resilient ring sufficiently compressible to be delivered transorally, and sufficiently large to spring outward into contact with the lower stomach adjacent the pyloric sphincter; a duodenal anchoring member comprising a plurality of resilient rings sufficiently compressible to be delivered transorally, and sufficiently large to spring outward into contact with a duodenal bulb area of the duodenum; and an elongated duodenal sleeve for placement in the duodenum having a tubular body with proximal and distal ends, the proximal end extending to the stomach anchoring member on the stomach side of the pyloric sphincter, and forming a compressible channel through the pyloric sphincter; wherein the device is formed of a material that will resist structural degradation over a period of at least six months within the gastrointestinal tract. - View Dependent Claims (15, 16, 17, 18, 19, 20, 21)
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Specification