METHODS OF PROVIDING THERAPEUTIC EFFECTS USING CYCLOSPORIN COMPONENTS
2 Assignments
0 Petitions
Accused Products
Abstract
Methods of treating an eye of a human or animal include administering to an eye of a human or animal a composition in the form of an emulsion including water, a hydrophobic component and a cyclosporin component in a therapeutically effective amount of less than 0.1% by weight of the composition. The weight ratio of the cyclosporin component to the hydrophobic component is less than 0.8.
0 Citations
60 Claims
-
1-36. -36. (canceled)
-
37. A method of increasing tear production in the eye of a human, the method comprising topically administering to the eye of the human an emulsion at a frequency of twice a day, wherein the emulsion comprises cyclosporin A in an amount of about 0.05% by weight, polysorbate 80, Pemulen, water, and castor oil in an amount of about 1.25% by weight;
- and
wherein the topical ophthalmic emulsion is effective in increasing tear production. - View Dependent Claims (38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53)
- and
-
54. A method of treating KCS, the method comprising the step of topically administering to an eye of a human an emulsion at a frequency of twice a day, the emulsion comprising:
-
cyclosporin A in an amount of about 0.05% by weight; castor oil in an amount of about 1.25% by weight; polysorbate 80 in an amount of about 1.0% by weight; Pemulen in an amount of about 0.05% by weight; a tonicity component or a demulcent component in an amount of about 2.2% by weight; a buffer; and water; wherein the emulsion is effective in treating KCS. - View Dependent Claims (55, 56, 57, 58)
-
-
59. A method comprising:
-
administering an emulsion topically to the eye of a human having KCS, wherein the emulsion comprises; cyclosporin A in an amount of about 0.05% by weight; castor oil in an amount of about 1.25% by weight; polysorbate 80 in an amount of about 1.0% by weight; Pemulen in an amount of about 0.05% by weight; glycerine in an amount of about 2.2% by weight; sodium hydroxide; and water; and wherein the emulsion is effective in increasing tear production in the human having KCS. - View Dependent Claims (60)
-
Specification