ADAPTIVE CALIBRATION SYSTEM FOR SPECTROPHOTOMETRIC MEASUREMENTS

• US 20140051953A1
• Filed: 10/28/2013
• Published: 02/20/2014
• Est. Priority Date: 09/28/2009
• Status: Abandoned Application

• Current Assignee: Willow Laboratories Incorporated
• Original Assignee: Cercacor Laboratories
• Inventors: Lamego, Marcelo, Merritt, Sean, Kiani, Massi Joe E.
• Application Number:
  US14/065,226
• Publication Number:
  US 20140051953A1
• Time in Patent Office: Days
• US Class Current: 600/316
• CPC Class Codes: A61B 5/14503 invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors A61B5/1459, A61B5/1464, A61B5/1473, A61B5/1482, A61B5/14865 take precedence
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/14546 for measuring analytes not otherwise provided for, e.g. ions, cytochromes
• CPC Class Codes: A61B 5/1455 using optical sensors, e.g. spectral photometrical oximeters
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/1495 Calibrating or testing of in-vivo probes
• CPC Class Codes: A61B 5/7221 Determining signal validity, reliability or quality A61B5/7207 and A61B5/7217 take precedence
• CPC Class Codes: A61B 5/742 using visual displays A61B5/339 takes precedence
• CPC Class Codes: A61B 5/746 Alarms related to a physiological condition, e.g. details of setting alarm thresholds or avoiding false alarms alarms per se G08B

Abstract

This disclosure describes, among other features, systems and methods for customizing calibration curves, parameter algorithms, and the like to individual users. An initial calibration curve generated based on a population can be used as a starting point in an algorithm for measuring a physiological parameter such as glucose. The measurement algorithm can determine one or more initial measurement values for a user based on the initial calibration curve. In certain embodiments, one or more alternative measurements, such as invasive or minimally invasive measurements, can periodically or sporadically be input into the measurement algorithm. The algorithm can use the alternative measurements to adapt the calibration curve to the individual. As a result, measurements for the individual can more accurately reflect the individual'"'"'s actual parameter values.

Claims

1. A method of determining whether to recommend an alternative measurement of a physiological parameter, the method comprising:

obtaining a noninvasive measurement of a physiological parameter using an optical sensor;

receiving an alternative measurement of the physiological parameter, the alternative measurement being generated by an alternative sensor;

analyzing the noninvasive and alternative measurements by a processor to determine whether a condition has been met; and

in response to the condition being met, outputting an indication that a new measurement should be obtained from the alternative sensor.

2. The method of claim 1, wherein analyzing the noninvasive and alternative measurements to determine whether a condition has been met comprises determining whether a difference between the noninvasive and alternative measurements exceeds a threshold.

3. The method of claim 1, wherein analyzing the noninvasive and alternative measurements to determine whether a condition has been met comprises determining a predetermined amount of time has passed.

4. The method of claim 1, wherein the indication comprises an alarm.

5. The method of claim 1, further comprising displaying the alternative measurement.

6. The method of claim 1, wherein the alternative source comprises an invasive monitor.

7. The method of claim 1, wherein the alternative source comprises a minimally-invasive monitor.

8. The method of claim 1, wherein the physiological parameter is glucose.