SYRINGE FOR MISING AND DISPENSING ADIPOSE TISSUE

• US 20140052059A1
• Filed: 08/14/2013
• Published: 02/20/2014
• Est. Priority Date: 08/14/2012
• Status: Active Grant

• Current Assignee: Allergan, Inc. (Canada) (Abbvie Incorporated)
• Original Assignee: Allergan, Inc. (Canada) (Abbvie Incorporated)
• Inventors: Schwab, Justin, Kayda, Edwin
• Granted Patent: US 9,095,654 B2
• Time in Patent Office: Days
• US Class Current: 604/82
• CPC Class Codes: A61M 2005/2414 from the side
• CPC Class Codes: A61M 2005/3128 Incorporating one-way valves, e.g. pressure-relief or non-return valves
• CPC Class Codes: A61M 2202/0021 removed from and reintroduced into the body, e.g. after treatment
• CPC Class Codes: A61M 2202/08 Lipoids
• CPC Class Codes: A61M 2205/276 preventing unwanted use
• CPC Class Codes: A61M 5/19 having more than one chamber , e.g. including a manifold coupling two parallelly aligned syringes through separate channels to a common discharge assembly surgical glue applicators A61B17/00491
• CPC Class Codes: A61M 5/315 Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
• CPC Class Codes: A61M 5/50 having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile retractable needles or needle protectors with means for preventing re-use A61M5/321

Abstract

A device is provided for introducing into a patient a combination of adipose tissue and an additive, for example, a hydrogel additive. The device includes a fat cartridge, an additive cartridge containing an additive, and a housing configured to receive, in a side-by-side manner, the fat cartridge and additive cartridge. A mixing tip may be included for causing mixing of the cartridge components prior to extrusion from a needle or cannula.

Claims

1. A device for introducing into a target region of a patient, a combination of adipose tissue and an additive, the device comprising:

a fat cartridge;

an additive cartridge;

a housing configured to receive, in a side-by-side manner, the fat cartridge and additive cartridge;

a mixing tip on the housing, the mixing tip including a distal end for receiving a cannula or needle; and

a plunger assembly including a fat cartridge plunger and an additive cartridge plunger, configured to be slidably received in the fat cartridge and the additive cartridge, respectively.

2. The device of claim 1 wherein the fat cartridge plunger and the additive cartridge plunger are fixed with respect to each other.

3. The device of claim 2 wherein the fat cartridge plunger and the additive cartridge plunger are fixed together at a proximal end of the plunger assembly.

4. The device of claim 1 wherein the housing is configured to receive the fat cartridge and the additive cartridge in a longitudinally slidable manner.

5. The device of claim 1 wherein the housing is configured to receive the fat cartridge and the additive cartridge in a lateral manner.

6. The device of claim 1 further comprising a mechanism for preventing extrusion of additive from the additive cartridge without extrusion of fat from the fat cartridge.

7. The device of claim 1 wherein the additive cartridge contains an additive.

8. The device of claim 7 wherein the additive comprises hyaluronic acid and collagen.

9. The device of claim 7 wherein the additive comprises hyaluronic acid crosslinked with collagen.

10. A device for introducing into a target region of a patient, a combination of adipose tissue and an additive, the device comprising:

a fat cartridge;

an additive cartridge including an additive;

a housing configured to receive, in a side-by-side manner, the fat cartridge and additive cartridge;

a mixing tip on the housing, the mixing tip including a distal end for receiving a cannula or needle;

a plunger assembly including a fat cartridge plunger and an additive cartridge plunger fixed with respect to each other and configured to be slidably received in the fat cartridge and the additive cartridge, respectively; and

a mechanism for preventing extrusion of additive from the additive cartridge without coextrusion of fat from the fat cartridge.

11. The device of claim 10 wherein the additive comprises hyaluronic acid crosslinked with collagen.

12. A device for administering a formulation comprising an adipose tissue and an additive, the device comprising:

(a) a first cartridge for containing an adipose tissue;

(b) a second cartridge for containing an additive to be added to and mixed with the adipose tissue;

(c) a housing configured to substantially enclose in a side-by-side manner the first and the second cartridges;

(d) a mixing tip on the housing, the mixing tip including;

(i) a lumen,

(ii) a proximal end for receiving and conducting into the lumen the adipose tissue and the additive for mixing within the lumen;

(iii) a distal end for receiving a cannula or needle through which the formulation can be administered; and

(e) a plunger assembly including a first cartridge plunger and a second cartridge plunger, the plunger assembly configured to be slidably received in the first cartridge and in the second cartridge and the plunger assembly when actuated acting to push the adipose tissue, by the action of the first cartridge plunger, from the first cartridge into the lumen and to push the additive, by the action of the second cartridge plunger, from the second cartridge into the lumen, for the mixing therein.