Necroptosis Inhibitors and Methods of Use Therefor
First Claim
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1. A compound selected from the group consisting of a compound of any one of formulas I-XIV:
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Abstract
Described herein are compositions that inhibit the production of TNFα downstream of CD40 activation. As such, also described are various methods of using compositions exhibiting this activity for the treatment or prevention of inflammatory diseases associated with TNFα production or CD40 activation.
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181 Claims
- 1. A compound selected from the group consisting of a compound of any one of formulas I-XIV:
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2-170. -170. (canceled)
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174. A therapeutic method of treating an inflammatory disease or other disease for inhibition of CD40 mediated TNFα
- production, comprising administering to a subject an effective amount of a compound selected from the group consisting of;
- View Dependent Claims (178, 179)
- production, comprising administering to a subject an effective amount of a compound selected from the group consisting of;
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175. A therapeutic method of treating an inflammatory disease or other disease for inhibition of CD40 mediated TNFα
- production, comprising administering to a subject an effective amount of a compound selected from the group consisting of;
- View Dependent Claims (180, 181)
- production, comprising administering to a subject an effective amount of a compound selected from the group consisting of;
Specification