METHOD AND SYSTEM TO INDICATE GLYCEMIC IMPACTS OF INSULIN INFUSION PUMP COMMANDS

• US 20140074059A1
• Filed: 09/12/2012
• Published: 03/13/2014
• Est. Priority Date: 09/12/2012
• Status: Abandoned Application

• Current Assignee: Lifescan Incorporated (Duv Holding Corporation)
• Original Assignee: Lifescan Incorporated (Duv Holding Corporation)
• Inventors: HOWELL, Frances Wilson, RODBARD, David, MACLEOD, Janice
• Application Number:
  US13/612,506
• Publication Number:
  US 20140074059A1
• Time in Patent Office: Days
• US Class Current: 604/503
• CPC Class Codes: A61M 2005/14208 with a programmable infusion control system, characterised by the infusion program
• CPC Class Codes: A61M 2205/3553 remote, e.g. between patient's home and doctor's office
• CPC Class Codes: A61M 2205/3561 local, e.g. within room or hospital
• CPC Class Codes: A61M 2205/3592 using telemetric means, e.g. radio or optical transmission
• CPC Class Codes: A61M 5/14244 adapted to be carried by the patient, e.g. portable on the body
• CPC Class Codes: A61M 5/1723 using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00
• CPC Class Codes: G16H 20/17 delivered via infusion or injection
• CPC Class Codes: G16H 40/67 for remote operation

Abstract

Various methods and system to provide insight into how certain commands to a patient'"'"'s infusion pump impact glycemic control of the subject. These patterns help to identify very specific areas of glycemic excursions, enable patients and HCPs to more easily identify patterns of hypoglycemia and hyperglycemia in order to take steps to improve glycemic control of the person with diabetes.

Claims

1. A system for management of diabetes of a subject, the system comprising:

at least one glucose monitor for measurements of the glucose levels of the subject;

an insulin infusion pump configured for communication with the at least one glucose monitor and delivery of insulin to the subject; and

a controller in communication with at least the insulin infusion pump and the at least one glucose monitor, the controller being configured to receive or transmit data regarding glucose levels and dosing of insulin from the at least one glucose monitor and pump for analysis by the controller so that at least one of a plurality of patterns in glucose due to at least one of a plurality of pump commands is determined via the controller by;

determination of whether there is at least one glucose measurement made within a predetermined time interval after occurrence of one of a plurality of pump commands;

flag the at least one glucose measurement as a flagged high measurement whenever the at least one glucose measurement is equal to or greater than a high threshold;

flag the at least one glucose measurement as a flagged low measurement whenever the at least one glucose measurement is equal to or less than a low threshold;

calculate a percentage of flagged high glucose measurements from total glucose measurements made during the predetermined time interval over a plurality of days;

calculate a percentage of flagged low glucose measurement from total glucose measurements made during the predetermined time interval over a plurality of days;

annunciate at least a first message that a high glucose pattern has been detected in relation to the one of a plurality of pump commands whenever the percentage of flagged high glucose measurements is equal to or greater than a first percentage or a second message that a low glucose pattern has been detected in relation to the one of a plurality of pump commands whenever the percentage of flagged low glucose measurements is equal to or greater than a second percentage.

2. The system of claim 1, in which the plurality of pump commands comprises a command for:

a bolus based on a carbohydrate calculator, a bolus based on measured glucose values, an override of a programmed bolus, a programmed bolus, or a temporary basal rate.

3. The system of claim 1, in which the first percentage comprises about 50% and the second percentage comprises about 5%.

4. A method for managing diabetes of a subject with at least a glucose monitor and infusion pump, the method comprising:

conducting, with the glucose monitor, a plurality of glucose measurements of the subject;

storing the plurality of glucose measurements in a memory;

determining whether there is at least one glucose measurement made within a predetermined time interval after occurrence of one of a plurality of pump commands;

flagging the at least one glucose measurement as a flagged high measurement whenever the at least one glucose measurement is equal to or greater than a high threshold;

flagging the at least one glucose measurement as a flagged low measurement whenever the at least one glucose measurement is equal to or less than a low threshold;

calculating a percentage of flagged high glucose measurements from total glucose measurements made during the predetermined time interval over a plurality of days;

calculating a percentage of flagged low glucose measurement from total glucose measurements made during the predetermined time interval over a plurality of days;

annunciating at least a first message that a high glucose pattern has been detected in relation to the one of a plurality of pump commands whenever the percentage of flagged high glucose measurements is equal to or greater than a first percentage or a second message that a low glucose pattern has been detected in relation to the one of a plurality of pump commands whenever the percentage of flagged low glucose measurements is equal to or greater than a second percentage.

5. The method of claim 4, in which the calculating of the percentage of flagged high glucose measurements comprises dividing the number of flagged high glucose measurements by a total number of glucose measurements made during the predetermined time interval for a plurality of days multiplied by 100 and the calculating of the percentage of flagged low glucose measurements comprises dividing the number of flagged low glucose measurements by a total number of glucose measurements made during the predetermined time interval for a plurality of days multiplied by 100.

6. The method of claim 4, in which the plurality of pump commands comprises a command for:

a bolus based on a carbohydrate calculator, a bolus based on measured glucose values, an override of a programmed bolus, a programmed bolus, or a temporary basal rate.

7. The method of claim 4, in which the first percentage comprises about 50% and the second percentage comprises about 5%.

8. A method for managing diabetes of a subject with at least a glucose monitor and infusion pump, the method comprising:

conducting, with the glucose monitor, a plurality of glucose measurements of the subject;

storing the plurality of glucose measurements in a memory;

determining whether there is at least one glucose measurement made during a predetermined time period after occurrence of a pump suspend command and a second predetermined time period after occurrence of a pump resume command;

flagging the at least one glucose measurement as a flagged high measurement whenever the at least one glucose measurement is equal to or greater than a high threshold;

calculating a percentage of flagged high glucose measurements from total glucose measurements made during the first and second predetermined time periods over a plurality of days; and

annunciating a first message that a high glucose pattern has been detected in relation to the pump suspend command whenever the percentage of flagged high glucose measurements is equal to or greater than a first percentage.

9. The method of claim 8, in which the first and second time period comprise equal time intervals.

10. The method of claim 8, in which the first and second time period comprise unequal time intervals.

11. The method of claim 8, in which each of the first and second time periods comprises about one hour in duration.

12. The method of claim 8, in which the calculating of the percentage of flagged high glucose measurements comprises dividing the number of flagged high glucose measurements by a total number of glucose measurements made during the predetermined time periods for a plurality of days multiplied by 100.

13. The method of claim 8, in which the first percentage comprises about 50%.

14. A method for managing diabetes of a subject with at least a glucose monitor and infusion pump, the method comprising:

conducting, with the glucose monitor, a plurality of glucose measurements of the subject;

storing the plurality of glucose measurements in a memory;

determining whether there is at least one glucose measurement made within a predetermined time interval after occurrence of a pump prime command;

flagging the at least one glucose measurement as a flagged low measurement whenever the at least one glucose measurement is equal to or less than a low threshold;

calculating a percentage of flagged low glucose measurement from total glucose measurements made during the predetermined time interval over a plurality of days; and

annunciating a second message that a low glucose pattern has been detected in relation to the pump prime command whenever the percentage of flagged low glucose measurements is equal to or greater than a second percentage.

15. The method of claim 14, in which the calculating of the percentage of flagged low glucose measurements comprises dividing the number of flagged low glucose measurements by a total number of glucose measurements made during the predetermined time interval for a plurality of days multiplied by 100.

16. The method of claim 14, in which the second percentage comprises about 5%

17. The method of claim 14, in which the predetermined time interval comprises about 2 hours.