ADVANCED ANALYTE SENSOR CALIBRATION AND ERROR DETECTION
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Abstract
Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.
10 Citations
30 Claims
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1-10. -10. (canceled)
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11. A method for identifying failure of an analyte sensor using a sensor system using electronics coupled to an analyte sensor, comprising:
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generating a data stream indicative of an analyte concentration of a host by applying a bias voltage to a first analyte sensor at least partially positioned within tissue of a host; applying a time-varying signal to the first analyte sensor; measuring a signal response to the stimulus signal; analyzing the signal response to determine whether the signal response satisfies one or more predetermined sensor fault criteria; and initiating an error routine if the one or more predetermined sensor fault criteria are determined to be satisfied. - View Dependent Claims (12, 13, 14, 18, 19, 20)
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21. A system for monitoring an analyte concentration of a host using an analyte sensor, the system configured to also identify failure of the analyte sensor, the system comprising:
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an analyte sensor configured for transcutaneous implantation into a host; and sensor electronics coupled to the analyte sensor, the sensor electronics configured to; generate a data stream indicative of an analyte concentration of a host by applying a bias voltage to the analyte sensor, apply a time-varying signal to the analyte sensor, measure a signal response to the stimulus signal, analyze the signal response to determine whether the signal response satisfies one or more predetermined sensor fault criteria, and initiate an error routine if the one or more predetermined sensor fault criteria are determined to be satisfied. - View Dependent Claims (22, 23, 24, 25, 26, 27, 28, 29, 30)
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Specification