ORAL PHARMACEUTICAL DISPERSION COMPOSITIONS
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Accused Products
Abstract
The invention provides an oral pharmaceutical composition, optionally in dose unit form, comprising a lipophilic drug substance in dispersion in a physiologically tolerable aqueous carrier, preferably an aqueous gel, wherein said drug substance contains a functional electrostatic group having a pKa value of from 2 to 10, characterised in that said aqueous carrier has a pH at least 0.3 below or above said pKa value, said pH being below said pKa where said group is acidic and above said pKa where said group is basic.
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Citations
20 Claims
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1-12. -12. (canceled)
- 13. An oral pharmaceutical composition in dose unit form, comprising a lipophilic drug substance in dispersion in a physiologically tolerable aqueous carrier, wherein said drug substance is ibuprofen or ketoprofen, and said aqueous carrier comprises a continuous aqueous gel having a pH in the range 4 to 4.5.
Specification