NANOPARTICLE AND POLYMER FORMULATIONS FOR THYROID HORMONE ANALOGS, ANTAGONISTS, AND FORMULATIONS THEREOF
First Claim
Patent Images
1. A composition comprising:
- a thyroid hormone analog conjugated to a polymer;
a morphogenic protein; and
a bioresorbable carrier.
1 Assignment
0 Petitions
Accused Products
Abstract
Disclosed are methods of treating subjects having conditions related to angiogenesis including administering an effective amount of a polymeric Nanoparticle form of thyroid hormone agonist, partial agonist or an antagonist thereof, to promote or inhibit angiogenesis in the subject. Compositions of the polymeric forms of thyroid hormone, or thyroid hormone analogs, are also disclosed.
-
Citations
20 Claims
-
1. A composition comprising:
-
a thyroid hormone analog conjugated to a polymer; a morphogenic protein; and a bioresorbable carrier. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
-
-
10. A method for treating a degenerative pathology of the central nervous system comprising:
-
conjugating a thyroid hormone analog to a polymer; encapsulating the polymer in a liposome, microparticle or nanoparticle; administering to a person in need thereof a therapeutic amount of the conjugated thyroid hormone analog. - View Dependent Claims (11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
-
Specification