Valve Prosthesis Frames

• US 20140200660A1
• Filed: 01/14/2013
• Published: 07/17/2014
• Est. Priority Date: 01/14/2013
• Status: Active Grant

• Current Assignee: Medtronic CV Luxembourg SARL (Medtronic Plc)
• Original Assignee: Medtronic CV Luxembourg SARL (Medtronic Plc)
• Inventors: DeStefano, Alaena, Dwork, Joshua, Gosal, Devin, Punga, Karan, Rinne, Finn, Savage, Padraig, Callol, Joseph, Tam, Billy
• Granted Patent: US 10,617,517 B2
• Time in Patent Office: Days
• US Class Current: 623/2.17
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2002/91558 connected peak to peak
• CPC Class Codes: A61F 2220/005 using adhesives
• CPC Class Codes: A61F 2230/0013 Horseshoe-shaped, e.g. crescent-shaped, C-shaped, U-shaped
• CPC Class Codes: A61F 2230/005 Rosette-shaped, e.g. star-shaped
• CPC Class Codes: A61F 2230/0054 V-shaped
• CPC Class Codes: A61F 2230/0078 hyperboloidal
• CPC Class Codes: A61F 2230/008 paraboloidal
• CPC Class Codes: A61F 2250/0037 differing in height or in length

Abstract

A prosthesis can include a collapsible, reexpandable frame comprising first, second, and third sets of struts that define first and second rows of expandable cells. In some embodiments, the struts of the first, second, and third set of struts can be tapered. In some embodiments, the frame can include an intermediate section and an inflow section that is proximal to the intermediate section. The inflow section can include a concave saddle portion that is adjacent the intermediate section, and an outwardly flared portion.

Claims

1. A prosthesis comprising:

a collapsible and re-expandable frame, the frame having an inflow edge and a longitudinal axis, the frame comprising;

first, second, and third sets of struts;

wherein struts of the first set of struts are connected to adjacent struts of the first set of struts at a first plurality of nodes at the inflow edge;

wherein the first and second sets of struts are connected at a second plurality of nodes to define a first row of expandable cells;

wherein the second and third sets of struts are connected at a third plurality of nodes to define a second row of expandable cells, the first row of expandable cells being proximal to the second row of expandable cells;

wherein each node of the second plurality of nodes has a first length;

wherein each node of the third plurality of nodes has a second length; and

wherein the first length is longer than the second length.

2. The prosthesis of claim 1, wherein:

the first length ranges from about 3 mm to about 7 mm; and

the second length ranges from about 2.5 mm to about 6.5 mm.

3. The prosthesis of claim 1, wherein a third length between centers of the first plurality of nodes and centers of the second plurality of nodes is longer than a fourth length between the centers of the second plurality of nodes and centers of the third plurality of nodes.

4. The prosthesis of claim 3, wherein the third and fourth lengths range from about 2.5 mm to about 6.5 mm.

5. The prosthesis of claim 1, wherein:

each strut of the first set comprises a proximal segment with a first width, an intermediate segment with a second width, and a distal segment with a third width;

the first width is smaller than the second width; and

the second width is smaller than the third width.

6. The prosthesis of claim 1, wherein:

each strut of the first set of struts comprises a first proximal segment, a first intermediate segment with a first width, and a first distal segment;

each strut of the second set of struts comprises a second proximal segment, a second intermediate segment with a second width, and a second distal segment; and

the second width is greater than the first width.

7. The prosthesis of claim 6, wherein the first and second widths range from about 0.1 mm to about 1.2 mm.

8. The prosthesis of claim 1, wherein each of the first plurality of nodes comprise a keyhole-shaped opening.

9. The prosthesis of claim 1, wherein:

the first row of expandable cells forms an outwardly flared portion at the inflow edge of the frame; and

the second row of expandable cells forms a concave saddle portion that is adjacent and distal to the outwardly flared portion.

10. The prosthesis of claim 1, wherein:

the frame further comprises a plurality of coupling elements at an outflow edge of the frame; and

struts circumferentially aligned with the coupling elements are configured to be less stiff than struts not circumferentially aligned with the coupling elements.

11. The prosthesis of claim 10, wherein a width or thickness of the struts circumferentially aligned with the coupling element is smaller than a respective width or thicknesses of the struts that are not circumferentially aligned with the coupling elements.

12. The prosthesis of claim 10, wherein a length, width, or thickness of nodes connecting the struts circumferentially aligned with the coupling elements are smaller than a respective length, width, or thickness of nodes connecting the struts that are not axially aligned with the coupling elements.

13. The prosthesis of claim 1, further comprising a valve body coupled to the frame.