BODY-WORN SYSTEM FOR MEASURING CONTINUOUS NON-INVASIVE BLOOD PRESSURE (cNIBP)
First Claim
1. A system for measuring a blood pressure value from a patient, comprising:
- (a) a first sensor configured to generate a first time-dependent waveform indicative of one or more contractile properties of the patient'"'"'s heart;
(b) a second sensor configured to generate a second time-dependent waveform indicative of one or more contractile properties of the patient'"'"'s heart;
(c) a third sensor configured to generate a third time-dependent waveform indicative of pressure applied to a patient'"'"'s arm; and
(d) a processing component configured to be worn on the patient'"'"'s body and comprising a microprocessor and a serial transceiver, the processing component programmed to;
(i) communicate through a cable worn on the patient'"'"'s body with a microprocessor and serial transceiver comprised by the first sensor to receive a digitized version of the first time-dependent waveform;
(ii) communicate with a microprocessor and serial transceiver comprised by the third sensor to receive a digitized version of the third time-dependent waveform;
(iii) calculate a pulse transit time calculated using a time difference between time-dependent features in digitized versions of the first and second time-dependent waveforms;
(iv) calculate a calibration from a relationship between pulse transit time and blood pressure combined with pressure values corresponding to at least one of systolic, diastolic, and mean arterial blood pressure, the calibration and pressure values determined from a digitized version of the third time-dependent waveform; and
(v) calculate the blood pressure value from the pulse transit time and the calibration.
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Accused Products
Abstract
The present invention provides a technique for continuous measurement of blood pressure based on pulse transit time and which does not require any external calibration. This technique, referred to herein as the ‘Composite Method’, is carried out with a body-worn monitor that measures blood pressure and other vital signs, and wirelessly transmits them to a remote monitor. A network of body-worn sensors, typically placed on the patient'"'"'s right arm and chest, connect to the body-worn monitor and measure time-dependent ECG, PPG, accelerometer, and pressure waveforms. The disposable sensors can include a cuff that features an inflatable bladder coupled to a pressure sensor, three or more electrical sensors (e.g. electrodes), three or more accelerometers, a temperature sensor, and an optical sensor (e.g., a light source and photodiode) attached to the patient'"'"'s thumb.
66 Citations
1 Claim
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1. A system for measuring a blood pressure value from a patient, comprising:
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(a) a first sensor configured to generate a first time-dependent waveform indicative of one or more contractile properties of the patient'"'"'s heart; (b) a second sensor configured to generate a second time-dependent waveform indicative of one or more contractile properties of the patient'"'"'s heart; (c) a third sensor configured to generate a third time-dependent waveform indicative of pressure applied to a patient'"'"'s arm; and (d) a processing component configured to be worn on the patient'"'"'s body and comprising a microprocessor and a serial transceiver, the processing component programmed to;
(i) communicate through a cable worn on the patient'"'"'s body with a microprocessor and serial transceiver comprised by the first sensor to receive a digitized version of the first time-dependent waveform;
(ii) communicate with a microprocessor and serial transceiver comprised by the third sensor to receive a digitized version of the third time-dependent waveform;
(iii) calculate a pulse transit time calculated using a time difference between time-dependent features in digitized versions of the first and second time-dependent waveforms;
(iv) calculate a calibration from a relationship between pulse transit time and blood pressure combined with pressure values corresponding to at least one of systolic, diastolic, and mean arterial blood pressure, the calibration and pressure values determined from a digitized version of the third time-dependent waveform; and
(v) calculate the blood pressure value from the pulse transit time and the calibration.
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Specification