GRADUAL TRANSITION BETWEEN BASAL RATES IN AN AMBULATORY DRUG DELIVERY DEVICE

• US 20140276570A1
• Filed: 03/15/2013
• Published: 09/18/2014
• Est. Priority Date: 03/15/2013
• Status: Abandoned Application

• Current Assignee: Tandem Diabetes Care Incorporated
• Original Assignee: Tandem Diabetes Care Incorporated
• Inventors: SAINT, SEAN
• Application Number:
  US13/837,777
• Publication Number:
  US 20140276570A1
• Time in Patent Office: Days
• US Class Current: 604/506
• CPC Class Codes: A61M 5/1723 using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00
• CPC Class Codes: G16H 20/17 delivered via infusion or injection

Abstract

A controller in an ambulatory drug delivery device automatically creates gradual transitions between basal rates entered by a user. The user may enter at least two target basal rates and two corresponding durations for delivering a medication at each rate. Systems and methods for such drug delivery are described.

Claims

1. A system for administering medication to a patient, comprising:

an infusion pump; and

software associated with the infusion pump configured to automatically provide a basal medication dosage profile that is based upon input from a user, the basal medication dosage profile comprising

at least two target basal rates;

a first duration for administering a medication to the patient at a first target basal rate; and

a second duration for administering the medication at a second target basal rate; and

at least one transition period over which a delivered basal rate gradually transitions between the target basal rates.

2. The system of claim 1, wherein the transition period is automatically set by the software.

3. The system of claim 1, wherein the transition period is set by the user.

4. The system of claim 1, wherein the infusion pump is configured to administer the medication such that a first volume administered in a first dose is either the same as or is different from a second volume administered in a second dose.

5. The system of claim 1, wherein a slope of a plot of the basal medication dosage profile as basal rate versus time provided by the software is non-zero and not infinity over the at least one transition period.

6. The system of claim 1, wherein the at least one transition period occurs over a fixed time period.

7. The system of claim 1, wherein the basal medication dosage profile includes at least two transition periods and each transition period has a duration that is constant within the basal medication dosage profile.

8. The system of claim 7, wherein the infusion pump is configured to administer medication doses at fixed time intervals.

9. The system of claim 8, wherein the duration of each transition period is an amount of time (T) that yields a whole number when divided by a duration (t) of the fixed dosage time intervals.

10. The system of claim 9, wherein the duration (t) of the fixed dosage time intervals is 5 minutes.

11. The system of claim 10, wherein the duration of each transition period (T) is 15 minutes, 30 minutes, 60 minutes, 90 minutes, or 120 minutes.

12. The system of claim 10, wherein the duration of each transition period (T) is 60 minutes.

13. The system of claim 1, wherein the user provides input using a user interface located on the infusion pump or on a remote device.

14. A method of delivering a medicament to a patient, comprising:

accepting, from a user via software associated with an infusion pump, at least two rates of medicament delivery and periods of time during a 24 hour period corresponding to each rate of medicament delivery;

generating a rate profile based upon the at least two rates of medicament delivery and periods of time using the software associated with the infusion pump; and

providing the rate profile to a controller associated with the infusion pump to direct administration of the medicament to the patient,

wherein the rate profile comprises a transition period between the at least two rates of medicament delivery over which a delivered rate gradually transitions between the two rates.

15. The method of claim 14, wherein the transition period has a duration chosen by the user.

16. The method of claim 14, wherein the transition period has a duration automatically determined by the software.

17. The method of claim 14, wherein the infusion pump is configured to administer medicament doses at fixed time intervals.

18. The method of claim 17, wherein the duration of each transition period is an amount of time (T) that yields a whole number when divided by a duration (t) of the fixed dosage time intervals.

19. The system of claim 18, wherein the duration (t) of the fixed dosage time intervals is 5 minutes.

20. The system of claim 14, wherein the pump administers the medication in a different volume for each dose administered during transition periods.

21. The method of claim 14, further comprising further refining the basal rate profile.

22. The method of claim 21, wherein further refining the basal rate profile comprises the user providing additional information.

23. The method of claim 22, wherein the additional information comprises more basal rate intervals, new values for existing basal rate intervals, or both.