PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-CHLORO-6-(SUBSTITUTED)PICOLINATES

• US 20140296533A1
• Filed: 06/13/2014
• Published: 10/02/2014
• Est. Priority Date: 12/13/2012
• Status: Active Grant

• Current Assignee: Dow Agrosciences LLC (Corteva, Inc.)
• Original Assignee: Dow Agrosciences LLC (Corteva, Inc.)
• Inventors: Renga, James M., Whiteker, Gregory T., Johnson, Peter L., Galliford, Christopher
• Granted Patent: US 9,822,077 B2
• Time in Patent Office: Days
• US Class Current: 546/250
• CPC Class Codes: C07C 251/12 being acyclic
• CPC Class Codes: C07D 213/72 Nitrogen atoms nitro radicals C07D213/61
• CPC Class Codes: C07D 213/73 Unsubstituted amino or imino radicals
• CPC Class Codes: C07D 213/74 Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
• CPC Class Codes: C07D 213/79 Acids; Esters
• CPC Class Codes: C07D 213/803 Processes of preparation

Abstract

4-Amino-5-fluoro-3-chloro-6-(substituted)picolinates are prepared from trifluoroacetic acid, p-methoxyaniline, a 3,3-dialkoxyprop-1-yne and a substituted methylene amine by a series of steps.

Claims

1. A process for the preparation of a 4-amino-5-fluoro-3-chloro-6-(substituted)picolinate of the Formula I

2. A compound of Formula C

3. A compound of Formula E

4. A compound of Formula G

5. A compound of Formula H