METHOD OF INCREASING THE HYDRODYNAMIC VOLUME OF POLYPEPTIDES BY ATTACHING TO GONADOTROPHIN CARBOXY TERMINAL PEPTIDES
1 Assignment
0 Petitions
Accused Products
Abstract
This invention is directed to the use of a chorionic gonadotrophin carboxy terminal peptide (CTP) or fragments thereof for modifying a polypeptide or a fragment thereof in order to increase the hydrodynamic volume of the polypeptide or fragment thereof.
18 Citations
99 Claims
-
1-64. -64. (canceled)
- 65. A method of increasing the hydrodynamic size or hydrodynamic volume of a polypeptide of interest or a fragment thereof, the method comprising attaching one to ten chorionic gonadotrophin carboxy terminal peptides (CTPs) to said polypeptide or fragment thereof, thereby increasing the hydrodynamic size or hydrodynamic volume of said polypeptide or fragment thereof.
Specification