PERIVALVULAR SEALING FOR TRANSCATHETER HEART VALVE

• US 20140343671A1
• Filed: 08/04/2014
• Published: 11/20/2014
• Est. Priority Date: 07/15/2011
• Status: Active Grant

• Current Assignee: Edwards Lifesciences Corporation
• Original Assignee: Edwards Lifesciences Corporation
• Inventors: Yohanan, Ziv, Gurovich, Nikolay, Felsen, Bella, Pelled, Itai, Meiri, Oded
• Granted Patent: US 10,028,826 B2
• Time in Patent Office: Days
• US Class Current: 623/2.18
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2/2436 Deployment by retracting a sheath
• CPC Class Codes: A61F 2220/0075 sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable
• CPC Class Codes: A61F 2230/0054 V-shaped
• CPC Class Codes: A61F 2250/0065 telescopic
• CPC Class Codes: A61F 2250/0069 Sealing means

Abstract

The present disclosure is directed to embodiments of catheter-based prosthetic heart valves, and in particular, prosthetic heart valves having sealing devices configured to seal the interface between the prosthetic valve and the surrounding tissue of the native annulus in which the prosthetic valve is implanted. In one embodiment, a prosthetic heart valve includes an annular sealing member that can be placed in a delivery orientation extending axially away from one end of the valve when the valve is in a radially compressed state. When the valve is expanded, the expansion of the frame causes the sealing member to be pulled to an operative orientation covering a portion of the frame. The present disclosure also discloses new mechanisms and techniques for mounting valve leaflets to a frame of a prosthetic heart valve.

Claims

1. A prosthetic heart valve comprising:

a collapsible and expandable annular frame that is configured to be collapsed to a radially collapsed state for mounting on a delivery apparatus and expanded to a radially expanded state inside the body, the frame having an inflow end, an outflow end, and a longitudinal axis extending from the inflow end to the outflow end, the frame comprising a plurality of struts defining a plurality of cells;

a collapsible and expandable valve member mounted within the annular frame; and

a collapsible and expandable annular sealing member coupled to the frame, the sealing member comprising an annular first portion secured to the struts on the outside of the frame and a second portion comprising a plurality of circumferentially spaced apart flaps that are free to pivot relative to the frame, wherein the flaps comprise a fabric that is heat set such that the flaps extend radially outwardly from the frame when the frame is in the radially expanded state.

2. The prosthetic heart valve of claim 1, wherein the flaps can be folded against the annular first portion of the sealing member when the frame is in the radially collapsed state.

3. The prosthetic heart valve of claim 1, wherein the flaps extend radially outwardly from the inflow end of the frame.

4. The prosthetic heart valve of claim 1, wherein the flaps are not supported by any metal supports extending outwardly from the frame.

5. The prosthetic heart valve of claim 1, wherein the sealing member comprises a first sealing member and the prosthetic heart valve comprises a second annular sealing member, the second annular sealing member comprising a plurality of circumferentially spaced apart flaps that are free to pivot relative to the frame, the flaps of the second sealing member being circumferentially offset from the flaps of the first sealing member such that the flaps of the second sealing member are aligned with the spaces between the flaps of the first sealing member.

6. The prosthetic heart valve of claim 1, wherein the sealing member comprises a polyethylene terephthalate fabric.

7. The prosthetic heart valve of claim 1, wherein the flaps extend longitudinally away from the inflow end of the frame to avoid overlapping the frame when the frame is in the radially collapsed state.