NATURAL COMBINATION HORMONE REPLACEMENT FORMULATIONS AND THERAPIES
9 Assignments
0 Petitions
Accused Products
Abstract
Estrogen and progesterone replacement therapies are provided herein. Among others, the following formulations are provided herein: solubilized estradiol without progesterone; micronized progesterone without estradiol; micronized progesterone with partially solubilized progesterone; solubilized estradiol with micronized progesterone; solubilized estradiol with micronized progesterone in combination with partially solubilized progesterone; and solubilized estradiol with solubilized progesterone.
41 Citations
7 Claims
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1. (canceled)
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2. A pharmaceutical formulation comprising solubilized estradiol, suspended progesterone, and a medium chain solubilizing agent;
- wherein each of the estradiol and the suspended progesterone are present in the solubilizing agent and the estradiol and the suspended progesterone are uniformly dispersed;
wherein at least about 90% of the estradiol is solubilized in the solubilizing agent; and
wherein the solubilizing agent comprises an effective amount of a C6-C12 oil. - View Dependent Claims (3, 4, 5, 6, 7)
- wherein each of the estradiol and the suspended progesterone are present in the solubilizing agent and the estradiol and the suspended progesterone are uniformly dispersed;
Specification