METHODS FOR CONTROLLING THE GALACTOSYLATION PROFILE OF RECOMBINANTLY-EXPRESSED PROTEINS

  • US 20150050693A1
  • Filed: 09/22/2014
  • Published: 02/19/2015
  • Est. Priority Date: 04/27/2011
  • Status: Active Grant
First Claim
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1. A process for producing adalimumab, comprising culturing a mammalian cell capable of producing adalimumab in a chemically defined cell culture media that has been supplemented with a manganese supplement and a galactose supplement.

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