Dual Path Immunoassay Device

• US 20150056688A1
• Filed: 11/04/2014
• Published: 02/26/2015
• Est. Priority Date: 03/11/2005
• Status: Active Grant

• Current Assignee: Chembio Diagnostic Systems Incorporated (Chembio Diagnostics, Inc.)
• Original Assignee: Chembio Diagnostic Systems Incorporated (Chembio Diagnostics, Inc.)
• Inventors: Esfandiari, Javanbakhsh
• Granted Patent: US 9,784,734 B2
• Time in Patent Office: Days
• US Class Current: 435/287.2
• CPC Class Codes: G01N 33/538 by sorbent column, particles or resin strip , i.e. sorbent materials
• CPC Class Codes: G01N 33/5695 Mycobacteria
• CPC Class Codes: G01N 33/56988 HIV or HTLV

Abstract

Systems include test cells with sorbent material in a T-shape and defining a first flow path for a solution and a second flow path for a sample, and a test line or test site with immobilized antigens or antibodies or other ligand binding molecules located at the junction of the T. A housing houses the sorbent material and defines a first hole adjacent an end of the first flow path for receiving the solution and a second hole adjacent an end of the second flow path for receiving the sample.

Claims

1. A test device for use with a solution and for determining the presence of a ligand in a liquid sample, the test device comprising:

a first sorbent strip having a first end defining a solution receiving portion that receives the solution, and having a test site distant said first end having an immobilized ligand-binding mechanism thereon; and

a second sorbent strip perpendicular to said first sorbent strip, said second sorbent strip having a first end defining a sample receiving portion that receives the liquid sample, and a portion distant said first end and touching said first sorbent strip at or adjacent said test site such that liquid sample applied to said first end of said second sorbent strip laterally migrates over time to said first sorbent strip and does not immediately wet said first sorbent strip.

2. A test device according to claim 1, wherein:

said first sorbent strip supports a conjugate having a marker between said first end and said test site.