Medical Delivery Device With Regimen Identification Feature

• US 20150066429A1
• Filed: 04/17/2013
• Published: 03/05/2015
• Est. Priority Date: 04/17/2012
• Status: Active Grant

• Current Assignee: Novo Nordisk A/S
• Original Assignee: Novo Nordisk A/S
• Inventors: Nielsen, Ole C., Monrad, Michael, Moeller, Mads, Filholm, Torkil
• Granted Patent: US 9,734,302 B2
• Time in Patent Office: Days
• US Class Current: 702/177
• CPC Class Codes: A61J 1/00 Containers specially adapted for medical or pharmaceutical purposes capsules or the like for oral use A61J3/07; specially adapted for surgical or diagnostic appliances or instruments A61B50/30; containers for radioactive substances G21F5/00
• CPC Class Codes: A61J 2200/30 Compliance analysis for taking medication
• CPC Class Codes: A61J 2205/50 using icons or symbolic figures, e.g. by a graphical representation symbolising the type of pathology or the organ by an image
• CPC Class Codes: A61J 7/0076 Medicament distribution means with pill counting devices A61J7/02; with time indication A61J7/04; containers or packages with special means for dispensing contents B65D83/00
• CPC Class Codes: A61J 7/0436 resulting from removing a drug from, or opening, a container
• CPC Class Codes: A61J 7/049 automatically changing in response to a schedule deviation by the patient
• CPC Class Codes: A61M 15/00 Inhalators drug delivery in endotracheal tubes A61M16/04
• CPC Class Codes: A61M 15/008 Electronic counters
• CPC Class Codes: A61M 2005/3125 specific display means, e.g. to indicate dose setting
• CPC Class Codes: A61M 2205/3379 Masses, volumes, levels of fluids in reservoirs, flow rates
• CPC Class Codes: A61M 2205/3561 local, e.g. within room or hospital
• CPC Class Codes: A61M 2205/3592 using telemetric means, e.g. radio or optical transmission
• CPC Class Codes: A61M 2205/52 with memories providing a history of measured variating parameters of apparatus or patient
• CPC Class Codes: A61M 2205/70 with testing or calibration facilities
• CPC Class Codes: A61M 5/00 Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests vaccination appliances for veterinary use A61D1/025 ; tube connectors, tube couplings, valves or branch units specially adapted for medical use A61M39/00; containers specially adapted for medical or pharmaceutical purposes A61J1/00; combinations of vial and syringe for mixing or transferring their contents A61J1/20; holders for containers for collecting, storing or administering blood or medical fluids A61J1/16
• CPC Class Codes: A61M 5/178 Syringes
• CPC Class Codes: A61M 5/3129 Syringe barrels A61M5/3205 and A61M5/50 take precedence
• CPC Class Codes: A61M 5/31525 Dosing burettes, pipettes B01L3/02
• CPC Class Codes: G16H 20/17 delivered via infusion or injection
• CPC Class Codes: G16H 50/20 for computer-aided diagnosis, e.g. based on medical expert systems

Abstract

A drug delivery system comprising a controller adapted to detect when a given user-actuated operation being part of the expelling of an amount of drug is performed, record detected operations as a function of time, and estimate, based on recorded operations, time parameters for the detected operations, thereby providing time parameters for a medical regimen on which the detected operations are assumed to be based upon.

Claims

1. A drug delivery system adapted to estimate time parameters for a medical regimen comprising one or more administering events at a given time within a given period, comprising:

a controller,

a drug reservoir or structure for receiving a drug reservoir,

drug expelling structure for expelling an amount of drug from the reservoir,

wherein the expelling of an amount of drug requires at least one user-actuated operation to be performed, and

wherein the expelling of an amount of drug represents an administering event,

the controller being adapted to;

detect when a given user-actuated operation being part of the expelling of an amount of drug is performed,

record detected operations as a function of time, and

estimate, based on recorded operations, regimen time parameters for the detected operations, including;

the periodicity, and

a time or time window for each operation in the estimated period,

thereby providing estimated time parameters for a medical regimen on which the detected operations are assumed to be based upon.

2. A drug delivery system as in claim 1, the system being configured to be set in a programming mode and a non-programming mode, wherein operations are detected and recorded when in the programming mode.

3. A drug delivery system as in claim 1, the system being configured to dynamically estimate time parameters incorporating most recent detected and recorded operations.

4. A drug delivery system as in claim 1, wherein the controller comprises information about a number of predefined regimens, the estimated parameters being matched to the best-fitting pre-defined regimen if possible for a given predefined confidence level.

5. A drug delivery system as in claim 1, wherein the system comprises:

structure for receiving a drug reservoir,

structure for detecting an identifier provided on a received drug reservoir,

wherein the controller comprises information about at least two identifiers, each identifier being related with at least one predefined regimen, the estimated parameters being matched to the best-fitting predefined regimen if possible for a given predefined confidence level.

6. A drug delivery system as in claim 1, wherein the drug expelling structure comprises:

setting structure allowing a user to set a dose amount to be expelled, and

actuation structure for driving or releasing the drug expelling structure to expel the set dose.

7. A drug delivery system as in claim 6, wherein the controller is configured to detect the amount of drug expelled, the controller estimating for each action in an identified regimen an amount or a range of drug expelled.

8. A drug delivery system as in claim 6, wherein the system is configured to provide reminders to the user based on the estimated time parameters.

9. A drug delivery system as in claim 6, wherein the system is configured to provide warnings to the user based on the estimated time parameters and the actual use of the delivery system.

10. A drug delivery system as in claim 6, adapted to for a given time period calculate a compliance value based on calculated regimen time parameters and corresponding detected operations, the compliance value being indicative of the user'"'"'s adherence to the regimen, wherein the compliance value is calculated for a user-selectable time period.

11. A drug delivery system as in claim 6, adapted to for a given time period calculate a compliance value based on the calculated regimen time parameters and corresponding detected operations, the compliance value being indicative of the user'"'"'s adherence to the regimen, the drug delivery further being adapted to display compliance value information comprising icons selected in accordance with the degree of compliance.

12. A method adapted to estimate time parameters for a medical regimen comprising one or more administering events at a given time within a given period, comprising the steps:

providing a system comprising;

a controller,

a drug reservoir or structure for receiving a drug reservoir,

drug expelling structure for expelling an amount of drug from the reservoir,

wherein the expelling of an amount of drug requires at least one user-actuated operation to be performed, and

wherein the expelling of an amount of drug represents an administering event,

detecting when a given user-actuated operation being part of the expelling of an amount of drug is performed,

record detected operations as a function of time, and

estimate, based on recorded operations, regimen time parameters for the detected operations, including;

the periodicity, and

a time or time window for each operation in the estimated period,

thereby providing estimated time parameters for a medical regimen on which the detected operations are assumed to be based upon.