TECHNIQUES AND DEVICES ASSOCIATED WITH BLOOD SAMPLING

• US 20150087944A1
• Filed: 10/30/2014
• Published: 03/26/2015
• Est. Priority Date: 03/02/2009
• Status: Abandoned Application

• Current Assignee: Seventh Sense Biosystems, Inc.
• Original Assignee: Seventh Sense Biosystems, Inc.
• Inventors: Levinson, Douglas A., Bernstein, Howard, Chickering, Donald E. III, Davis, Shawn, Haghgooie, Ramin, Michelman, Mark
• Application Number:
  US14/527,923
• Publication Number:
  US 20150087944A1
• Time in Patent Office: Days
• US Class Current: 600/365
• CPC Class Codes: A61B 5/0013 Medical image data A61B1/00011, A61B6/56, A61B8/56 take precedence
• CPC Class Codes: A61B 5/0022 Monitoring a patient using a global network, e.g. telephone networks, internet
• CPC Class Codes: A61B 5/0077 Devices for viewing the surface of the body, e.g. camera, magnifying lens
• CPC Class Codes: A61B 5/1438 using pre-evacuated means
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/14539 for measuring pH
• CPC Class Codes: A61B 5/14546 for measuring analytes not otherwise provided for, e.g. ions, cytochromes
• CPC Class Codes: A61B 5/1459 invasive, e.g. introduced into the body by a catheter A61B5/1464 takes precedence
• CPC Class Codes: A61B 5/14865 invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
• CPC Class Codes: A61B 5/150022 for capillary blood or interstitial fluid
• CPC Class Codes: A61B 5/150099 by negative pressure, other than vacuum extraction into a syringe by pulling on the piston rod or into pre-evacuated tubes
• CPC Class Codes: A61B 5/150221 Valves
• CPC Class Codes: A61B 5/150358 Strips for collecting blood, e.g. absorbent optical reagent test strips G01N21/8483; chemical reagent test strips G01N33/4875, G01N33/52
• CPC Class Codes: A61B 5/150389 Hollow piercing elements, e.g. canulas, needles, for piercing the skin
• CPC Class Codes: A61B 5/150412 Pointed piercing elements, e.g. needles, lancets for piercing the skin blade-like piercing elements A61B5/150442
• CPC Class Codes: A61B 5/150442 Blade-like piercing elements, e.g. blades, cutters, knives, for cutting the skin
• CPC Class Codes: A61B 5/150503 Single-ended needles hollow piercing element tip design A61B5/150396, needle sets for catheters A61M25/06, needles for bringing media into the body A61M5/32
• CPC Class Codes: A61B 5/150969 Low-profile devices which resemble patches or plasters, e.g. also allowing collection of blood samples for testing
• CPC Class Codes: A61B 5/150984 Microneedles or microblades
• CPC Class Codes: A61B 5/151 Devices specially adapted for taking samples of capillary blood, e.g. by lancets , needles or blades
• CPC Class Codes: A61B 5/15125 : comprising a vacuum or compressed fluids
• CPC Class Codes: A61B 5/157 : Devices characterised by integrated means for measuring characteristics of blood
• CPC Class Codes: A61B 5/411 : Detecting or monitoring allergy or intolerance reactions to an allergenic agent or substance
• CPC Class Codes: A61B 5/4839 : combined with drug delivery
• CPC Class Codes: A61B 5/4845 : Toxicology, e.g. by detection of alcohol, drug or toxic products A61B5/4848 takes precedence
• CPC Class Codes: A61B 5/486 : Bio-feedback A61B5/375 takes precedence
• CPC Class Codes: A61B 5/685 : Microneedles
• CPC Class Codes: A61B 5/6898 : Portable consumer electronic devices, e.g. music players, telephones, tablet computers
• CPC Class Codes: A61B 5/743 : Displaying an image simultaneously with additional graphical information, e.g. symbols, charts, function plots

Abstract

The present invention generally relates to devices and techniques associated with diagnostics, therapies, and other applications, including skin-associated applications, for example, devices for delivering and/or withdrawing fluid from subjects, e.g., through the skin. In some embodiments, the device includes a system for accessing an extractable medium from and/or through the skin of the subject at an access site, and a pressure regulator supported by a support structure, able to create a pressure differential across the skin at at least a portion of the access site. The device may also include, in some cases, a sensor supported by the support structure for determining at least one condition of the extractable medium from the subject, and optionally a signal generator supported by the support structure for generating a signal relating to the condition of the medium determined by the sensor.

Claims

1-26. -26. (canceled)

27. A method, comprising:

receiving fluid from a subject in a device applied to the skin of the subject, the device comprising a microneedle and a vacuum chamber having an internal pressure less than atmospheric pressure before the device is applied to the skin of the subject, wherein the device is configured to produce a display based on the fluid received into the device; and

acquiring an image of the display using a cell phone.

28. The method of claim 27, further comprising determining an analyte within the fluid received into the device, wherein the display is based on the analyte.

29. The method of claim 28, wherein the display is a color display.

30. The method of claim 29, wherein the color of the display is based on the analyte.

31. The method of claim 28, wherein the analyte comprises glucose.

32. The method of claim 27, wherein the display can be analyzed quantitatively.

33. The method of claim 27, comprising acquiring the image of the display using a camera in the cell phone.

34. The method of claim 27, further comprising transmitting the image of the display to an external entity.

35. The method of claim 34, wherein the external entity sends a message regarding the analyte to the cell phone.

47. The method of claim 35, wherein the message comprises a prescription.

48. The method of claim 35, wherein the message causes the device to dispense a pharmaceutical to the subject.

36-46. -46. (canceled)

49. A device, comprising:

one or more microneedles;

a vacuum chamber having an internal pressure less than atmospheric pressure before the device is applied to the skin of the subject, wherein the vacuum chamber is configured to withdraw fluid from the subject into the device after application of the one or more microneedles to the subject;

a sensor configured to sense the fluid withdrawn into the device;

a display configured to display a signal based on sensing of the withdrawn fluid by the sensor; and

a cell phone configured to image the display.

50. The device of claim 49, wherein the sensor is configured to sense an analyte within the fluid withdrawn from the subject.

51. The device of claim 50, wherein the display displays a signal based on the analyte.

52. The device of claim 51, wherein the signal is quantitatively related to the analyte.

53. The device of claim 50, wherein the analyte comprises glucose.

54. The device of claim 49, wherein the display is a color display.

55. The device of claim 49, wherein the cell phone is configured to acquire an image of the display via a camera.

56. The device of claim 49, wherein the cell phone is configured to transmit the image of the display to an external entity.

57. The device of claim 49, wherein the device further comprises a storage chamber, separate from the vacuum chamber, for receiving the fluid from the subject.

58. The device of claim 49, wherein the fluid comprises blood.