SYSTEM AND METHOD FOR ESTIMATING TISSUE HEATING OF A TARGET ABLATION ZONE FOR ELECTRICAL-ENERGY BASED THERAPIES
First Claim
1. A method of treating a tissue with a medical treatment device that applies electrical treatment energy through one or more electrodes defining a target treatment area of the tissue and comprises a display device, the method comprising:
- providing one or more parameters of a treatment protocol for delivering one or more electrical pulses to a tissue through one or more electrodes;
modeling heat distribution and/or electric field distribution in a tissue surrounding the electrodes based on the one or more parameters;
displaying a graphical representation of the heat and/or electric field distribution based on the modeled heat distribution in the display device;
modifying one or more of the parameters of the treatment protocol based on the graphical representation of the heat distribution; and
implanting the electrodes in the tissue and delivering one or more electrical pulses to the tissue through the electrodes by way of a voltage pulse generator based on the one or more modified parameters.
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Accused Products
Abstract
Systems and methods are provided for modeling and for providing a graphical representation of tissue heating and electric field distributions for medical treatment devices that apply electrical treatment energy through one or a plurality of electrodes. In embodiments, methods comprise: providing one or more parameters of a treatment protocol for delivering one or more electrical pulses to tissue through a plurality of electrodes; modeling electric and heat distribution in the tissue based on the parameters; and displaying a graphical representation of the modeled electric and heat distribution. In another embodiment, a treatment planning module is adapted to generate an estimated target ablation zone based on a combination of one or more parameters for an irreversible electroporation protocol and one or more tissue-specific conductivity parameters.
60 Citations
22 Claims
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1. A method of treating a tissue with a medical treatment device that applies electrical treatment energy through one or more electrodes defining a target treatment area of the tissue and comprises a display device, the method comprising:
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providing one or more parameters of a treatment protocol for delivering one or more electrical pulses to a tissue through one or more electrodes; modeling heat distribution and/or electric field distribution in a tissue surrounding the electrodes based on the one or more parameters; displaying a graphical representation of the heat and/or electric field distribution based on the modeled heat distribution in the display device; modifying one or more of the parameters of the treatment protocol based on the graphical representation of the heat distribution; and implanting the electrodes in the tissue and delivering one or more electrical pulses to the tissue through the electrodes by way of a voltage pulse generator based on the one or more modified parameters. - View Dependent Claims (2)
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3. A method of treatment planning for medical therapies involving administering electrical treatment energy, the method comprising:
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providing one or more parameters of a treatment protocol for delivering one or more electrical pulses to tissue through one or more electrodes; modeling heat and/or electric field distribution in the tissue based on the parameters; and displaying a graphical representation of the modeled heat and/or electric field distribution. - View Dependent Claims (4, 5, 6, 7, 8, 9, 10, 11, 20, 21, 22)
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12. A system for treatment planning for medical therapies involving administering electrical treatment energy, the system comprising:
a computer comprising; a memory; a display device; a processor coupled to the memory and the display device; and a treatment planning module stored in the memory and executable by the processor, the treatment planning module adapted to; receive as input one or more parameters of a treatment protocol for delivering electrical pulses to tissue through one or more electrodes; model heat and/or electric field distribution in the tissue based on the parameters; display a graphical representation of the modeled heat and/or electric field distribution on the display device. - View Dependent Claims (13, 14, 15, 16, 17, 18, 19)
Specification