SYSTEMS AND METHODS FOR STATUS INDICATION IN A SINGLE-USE BIOMEDICAL AND BIOPROCESS SYSTEM

• US 20150137992A1
• Filed: 11/21/2013
• Published: 05/21/2015
• Est. Priority Date: 11/21/2013
• Status: Active Grant

• Current Assignee: Cytiva Sweden AB (Danaher Corporation)
• Original Assignee: GE Healthcare Bio-Sciences AB (General Electric Company)
• Inventors: Potyrailo, Radislav A., Gebauer, Klaus, Stridsberg-Friden, Kajsa, Wortley, Timothy A.
• Granted Patent: US 9,571,904 B2
• Time in Patent Office: Days
• US Class Current: 340/870.07
• CPC Class Codes: A61L 2/24 Apparatus using programmed or automatic operation
• CPC Class Codes: C12M 41/48 Automatic or computerized control automatic analysis G01N35/00
• CPC Class Codes: G01N 27/3272 Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels optical biosensors G01N33/52
• CPC Class Codes: G06K 19/0702 the arrangement including a battery
• CPC Class Codes: G06K 19/0707 the arrangement being capable of collecting energy from external energy sources, e.g. thermocouples, vibration, electromagnetic radiation G06K19/0702 takes precedence
• CPC Class Codes: G06K 19/07745 Mounting details of integrated circuit chips
• CPC Class Codes: G08B 21/18 Status alarms G08B21/02 takes precedence
• CPC Class Codes: H04Q 2209/30 using a wired architecture
• CPC Class Codes: H04Q 2209/47 using RFID associated with sensors
• CPC Class Codes: H04Q 9/00 Arrangements in telecontrol or telemetry systems for selectively calling a substation from a main station, in which substation desired apparatus is selected for applying a control signal thereto or for obtaining measured values therefrom

Abstract

Methods, systems, and apparatus to monitor component status in a bioprocessing environment are disclosed and described. Certain examples provide a sensor device for a disposable bioprocessing component. The example sensor device includes a first portion affixed to the component, the first portion configured to provide an identifier associated with the component. The example sensor device also includes a second portion configured to provide a status indication based on a state of the component. The example sensor device is configured to transmit the identifier and status indication to a control computer associated with a bioproces sing platform including the component.

Claims

1. A disposable bioprocessing component comprising:

a sensor comprising;

a first portion configured to provide an identifier; and

a second portion configured to provide a status indication based on a state of the component,

the identifier and status indication to be transmitted for use by a control system for a bioprocessing platform.

2. The component of claim 1, wherein the component comprises at least one of a clamp, valve, actuator, switch, connector, and lever.

3. The component of claim 1, wherein the status indication comprises at least one of a position, a level, and an indication of an open or closed state of the component.

4. The component of claim 1, wherein the sensor is removably mounted on the component.

5. The component of claim 1, wherein at least one of the first and second portions of the sensor is integrated in the component.

6. The component of claim 1, wherein the control system is to prompt an action based on the transmitted identifier and status indication, the action comprising at least one of a confirmation, an alert, an alarm, a recording, an instruction to change configuration of the component, and a change in operation of the control system.

7. The component of claim 1, wherein at least one of the first and second portions of the sensor comprises a radio frequency identification (RFID) tag.

8. The component of claim 7, wherein the RFID tag comprises a sterilizable RFID tag.

9. The component of claim 8, wherein sterilization is to be achieved by at least one of gamma irradiation, autoclaving, steam, electron beam, and gas.

10. The component of claim 7, wherein the RFID tag comprises at least one of a high frequency (HF) RFID tag, a low frequency (LF) RFID tag, and a near field communication (NFC) RFID tag.

11. The component of claim 1, wherein at least one of the first and second portions of the sensor comprises a barcode associated with an optical reader.

12. The component of claim 1, wherein the first portion of the sensor comprises a radio frequency identification tag and the second portion of the sensor comprises a wireless sensor node.

13. The component of claim 12, wherein the second portion activates the first portion to transmit the status indication when the second portion is brought into close proximity with the first portion.

15. The device of claim 11, wherein the component comprises at least one of a clamp, valve, actuator, switch, connector, and lever.

16. The device of claim 11, wherein the status indication comprises at least one of a position, a level, and an indication of an open or closed state of the component.

17. The device of claim 11, wherein the sensor is removably mounted on the component.

18. The device of claim 11, wherein at least one of the first and second portions of the sensor is integrated in the component.

19. The device of claim 11, wherein the control computer is to prompt an action based on the transmitted identifier and status indication, the action comprising at least one of an alert, an alarm, a recording, an instruction to change configuration of the component, and a change in operation of the bioprocessing platform.

20. The device of claim 11, wherein at least one of the first and second portions of the sensor comprises a radio frequency identification (RFID) tag.

21. The device of claim 11, wherein at least one of the first and second portions of the sensor comprises a barcode associated with an optical reader.

22. The device of claim 11, wherein the first portion of the sensor comprises a radio frequency identification tag and the second portion of the sensor comprises a wireless sensor node.

23. The device of claim 22, wherein the second portion activates the first portion to transmit the status indication when the second portion is brought into close proximity with the first portion.

14. A sensor device for a disposable bioprocessing component, the sensor device comprising:

a first portion affixed to the component, the first portion configured to provide an identifier associated with the component; and

a second portion configured to provide a status indication based on a state of the component,

the sensor device configured to transmit the identifier and status indication to a control computer associated with a bioprocessing platform including the component.

24. A method to monitor a component in a bioprocessing system including a bioprocessing subsystem and a control subsystem, said method comprising:

identifying the component based on feedback from a first portion of a sensor associated with the component;

determining a state of the component based on feedback from a second portion of the sensor associated with the component; and

facilitating triggering of an action based on the state and identification of the component provided wirelessly by the sensor.

25. A method of process control by monitoring a component in a bioprocessing system, said method comprising:

identifying the component based on feedback from a first portion of a sensor associated with the component;

determining an initial state of the component based on feedback from a second portion of the sensor associated with the component;

monitoring the process to identify a user action; and

facilitating triggering of an action based on the state and identification of the component provided wirelessly by the sensor.