ANALYTE CONCENTRATION ALERT FUNCTION FOR ANALYTE SENSOR SYSTEM

• US 20150141770A1
• Filed: 12/03/2014
• Published: 05/21/2015
• Est. Priority Date: 03/29/2012
• Status: Active Grant

• Current Assignee: Senseonics, Incorporated (Senseonics Holdings, Inc.)
• Original Assignee: Senseonics, Incorporated (Senseonics Holdings, Inc.)
• Inventors: DeHennis, Andrew, Rastogi, Ravi
• Granted Patent: US 10,327,714 B2
• Time in Patent Office: Days
• US Class Current: 600/301
• CPC Class Codes: A61B 2562/0219 Inertial sensors, e.g. accelerometers, gyroscopes, tilt switches
• CPC Class Codes: A61B 5/0002 Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network A61B5/07 takes precedence; transmission systems for measured values G08C; transmission H04B; transmission of digital information H04L; wireless communication networks H04W
• CPC Class Codes: A61B 5/0004 characterised by the type of physiological signal transmitted
• CPC Class Codes: A61B 5/01 Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue clinical contact thermometers G01K13/20
• CPC Class Codes: A61B 5/0533 Measuring galvanic skin response
• CPC Class Codes: A61B 5/1112 Global tracking of patients, e.g. by using GPS
• CPC Class Codes: A61B 5/1118 Determining activity level
• CPC Class Codes: A61B 5/145 Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissuemeasuring of blood pressure or blood flow A61B5/02; non-radiation detecting or locating of foreign bodies in blood A61B5/06
• CPC Class Codes: A61B 5/14503 invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors A61B5/1459, A61B5/1464, A61B5/1473, A61B5/1482, A61B5/14865 take precedence
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/1459 invasive, e.g. introduced into the body by a catheter A61B5/1464 takes precedence
• CPC Class Codes: A61B 5/6898 Portable consumer electronic devices, e.g. music players, telephones, tablet computers
• CPC Class Codes: A61B 5/7203 for noise prevention, reduction or removal
• CPC Class Codes: A61B 5/7282 Event detection, e.g. detecting unique waveforms indicative of a medical condition A61B5/4094, A61B5/4818, A61B5/349, A61B5/0823 take precedence
• CPC Class Codes: A61B 5/7405 using sound
• CPC Class Codes: A61B 5/742 using visual displays A61B5/339 takes precedence
• CPC Class Codes: A61B 5/7455 characterised by tactile indication, e.g. vibration or electrical stimulation
• CPC Class Codes: A61B 5/746 Alarms related to a physiological condition, e.g. details of setting alarm thresholds or avoiding false alarms alarms per se G08B

Abstract

Systems, methods, and apparatuses that provide alerts based on analyte data and acceleration data. An analyte sensor may generate the analyte data. An accelerometer may generate the acceleration data. A transceiver may convert the analyte data into analyte concentration values. The transceiver may convert the acceleration data into activity information. The transceiver may generate an alert based on the analyte concentration values and activity information. The alert may be communicated to a user by a mobile medical application executed on the transceiver and/or a display device (e.g., smartphone) in communication with the transceiver. The mobile medical application may display (e.g., on a display of the display device) a plot or graph of the analyte concentration values and activity information with respect to time.

Claims

1. A method of alerting for a current or projected physiological condition or reaction, the method comprising:

generating acceleration data corresponding to movement of an accelerometer;

generating activity information based on the acceleration data; and

generating an alert for the current or projected physiological condition or reaction based on the activity information.

2. The method of claim 1, further comprising displaying the alert.

3. The method of claim 2, further comprising generating a display of the alert by a mobile medical application executed by a processor of a display device.

4. The method of claim 3, wherein the display device is a smartphone.

5. The method of claim 1, wherein the accelerometer is located within a transceiver.

6. The method of claim 1, wherein the accelerometer is located within an analyte sensor.

7. The method of claim 1, wherein the accelerometer is located within an activity tracker.

8. The method of claim 1, further comprising receiving galvanic or physiologic measurements from an on-body or within body sensor, wherein the activity information is generated based on the acceleration data and the galvanic or physiologic measurements.

9. The method of claim 1, wherein the accelerometer is located in a transceiver, the method further comprises receiving activity information from an activity tracker, and the alert is additionally based on the activity information received from the activity tracker.

10. The method of claim 1, wherein the physiological condition or reaction is hypoglycemia.

11. The method of claim 1, wherein the physiological condition or reaction is dehydration.

12. The method of claim 1, wherein the physiological condition or reaction is hyperglycemia.

13. The method of claim 1, further comprising generating analyte concentration values based on data signals received from an analyte sensor;

wherein generating the alert comprises generating the alert based on the activity information and the analyte concentration values.

14. The method of claim 13, further comprising displaying a plot of the analyte concentration values and the activity information with respect to time.

15. The method of claim 14, wherein the plot is generated by a mobile medical application executed by a processor of a display device, and the plot is displayed on a display of the display device.

16. The method of claim 13, further comprising using a transceiver to receive the data signals from the analyte sensor.

17. The method of claim 16, further comprising using the transceiver to generate the analyte concentration values.

18. The method of claim 16, further comprising:

using the transceiver to convey the data signals to a display device; and

using a mobile medical application executed by a processor of the display device to generate the analyte concentration values.

19. The method of claim 1, wherein the alert is a predictive alert.

20. The method of claim 1, further comprising using the activity information to detect sleep patterns.

21. The method of claim 1, further comprising using the activity information to detect step counts.

22. The method of claim 1, wherein generating the activity information based on the acceleration information comprises:

converting the acceleration data into scalar acceleration values;

comparing the scalar acceleration values to an activity threshold; and

generating activity information based on the frequency of acceleration values that exceed the activity threshold.

23. The method of claim 1, further comprising using a transceiver to generate the activity information.

24. The method of claim 1, further comprising using a mobile medical application executed by a processor of a display device to generate the activity information.

25. The method of claim 1, further comprising using a transceiver to receive the generated activity information.

26. The method of claim 1, further comprising using a transceiver to generate the alert.

27. The method of claim 1, further comprising using a mobile medical application executed by a processor of a display device to generate the alert.

28. A system comprising:

an accelerometer configured to generate acceleration data corresponding to movement of the accelerometer; and

a transceiver configured to;

generate or receive activity information based on the acceleration data, and

generate an alert for a current or projected physiological condition or reaction based on the activity information.

29. The system of claim 28, wherein the transceiver comprises the accelerometer.

30. The system of claim 28, further comprising an analyte sensor.

31. The system of claim 30, wherein the analyte sensor comprises the accelerometer.

32. The system of claim 30, wherein the transceiver is configured to:

receive data signals from the analyte sensor,

generate analyte concentration values based on the received data signals, and

generate the alert based on the analyte concentration values, and the activity information.

33. The system of claim 32, further comprising a display configured to display the analyte concentration values and the activity information with respect to time.

34. The system of claim 33, wherein the display is configured to display a plot or graph of the analyte concentration values and the activity information with respect to time.

35. The system of claim 32, further comprising a display device including:

a transceiver interface device configured to receive the alert, the analyte concentration values, and the activity information from the transceiver;

a processor configured to execute a mobile medical application configured to generate a display of the alert, the analyte concentration values, and the activity information; and

a display configured to display the generated display.

36. The system of claim 28, wherein, to generate the activity information based on the acceleration data, the transceiver is configured to:

convert the acceleration data into scalar acceleration values;

compare the scalar acceleration values to an activity threshold; and

generate activity information based on the frequency of acceleration values that exceed the activity threshold.

37. The system of claim 28, further comprising an activity tracker.

38. The system of claim 37, wherein the activity tracker comprises the accelerometer.

39. The system of claim 37, wherein the transceiver comprises the accelerometer and is further configured to:

receive activity information from the activity tracker, and

generate the alert is based on (i) the activity information generated by the transceiver and (ii) the activity information received from the activity tracker.

40. The system of claim 28, wherein the transceiver is further configured to:

receive galvanic or physiologic measurements from an on-body or within body sensor, and

generate the activity information based on the acceleration data and the galvanic or physiologic measurements.

41. An apparatus comprising:

a sensor interface device configured to receive data signals from an analyte sensor;

an accelerometer configured to generate acceleration data corresponding to movement of the accelerometer; and

circuitry configured to

generate analyte concentration values based on the received data signals,

generate activity information based on the acceleration data, and

generate an alert based on the analyte concentration values and the activity information.

42. An apparatus comprising:

an interface device configured to receive analyte concentration values and activity information;

circuitry configured to generate a plot of the analyte concentration values and the activity information with respect to time; and

a display configured to display the plot.

43. A method of alerting for a current or projected physiological condition or reaction based on informatics generated by accelerometer measurements.