FENESTRATED PROSTHESIS

• US 20150173923A1
• Filed: 12/23/2014
• Published: 06/25/2015
• Est. Priority Date: 04/28/2009
• Status: Active Grant

• Current Assignee: Cleveland Clinic Foundation, Endologix
• Original Assignee: Cleveland Clinic Foundation, Endologix
• Inventors: Mayberry, Kevin, Clair, Daniel, Welk, Craig, Schreck, Stefan G.
• Granted Patent: US 10,603,196 B2
• Time in Patent Office: Days
• US Class Current: 1/1
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/856 Single tubular stent with a side portal passage
• CPC Class Codes: A61F 2/89 the wire-like elements comprising two or more adjacent rings flexibly connected by separate members
• CPC Class Codes: A61F 2/90 characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2/954 for placing stents or stent-grafts in a bifurcation
• CPC Class Codes: A61F 2/966 with relative longitudinal movement between outer sleeve and prosthesis, e.g. using a push rod
• CPC Class Codes: A61F 2/97 the outer sleeve being splittable
• CPC Class Codes: A61F 2002/061 provided with means for allowing access to secondary lumens
• CPC Class Codes: A61F 2002/065 Y-shaped blood vessels
• CPC Class Codes: A61F 2002/067 modular
• CPC Class Codes: A61F 2002/075 the stent being loosely attached to the graft material, e.g. by stitching
• CPC Class Codes: A61F 2002/9511 the retaining means being filaments or wires
• CPC Class Codes: A61F 2250/0039 differing in diameter
• CPC Class Codes: Y10T 29/49863 with prestressing of part

Abstract

Some embodiments of the present disclosure are directed to endoluminal prostheses having one or more reinforced fenestrations therein. The one or more reinforced fenestrations can have improved sealing capabilities with respect to branch grafts deployed within the fenestrations, improved tear resistance and expandability, and improved pull-out resistance for branch grafts. In some embodiments, the endoluminal prosthesis can have a main graft body defining a flow lumen therethrough, a first opening passing through a wall of the main graft body, and a first support member supported by the main graft body and overlapping an edge of the first opening, the first support member being configured to at least increase the tear resistance of the main graft body adjacent to the first opening. The support member can be stitched or otherwise attached to the main graft adjacent to the fenestration.

Claims

1-26. -26. (canceled)

27. An endoluminal prosthesis system comprising:

a delivery catheter having a flexible catheter body and a proximal and a distal end;

an endoluminal prosthesis comprising a main graft body having a lumen axially therethrough and a plurality of fenestrations in a wall portion of the main graft body, the plurality of fenestrations being in communication with the lumen, the plurality of fenestrations being offset from each other along a length of the main body graft; and

a plurality of guidewire sheaths, each of the plurality of guidewire sheaths being positioned through at least a portion of the lumen of the main graft body, and through a corresponding fenestration in the wall portion of the main graft body when the endoluminal prosthesis is in a collapsed, pre-delivery state within the catheter body.

28. The system of claim 28, wherein the plurality of fenestrations are longitudinally aligned.

29. The system of claim 28, wherein the plurality of fenestrations comprises a first fenestration, a second fenestration, and a third fenestration.

30. The system of claim 28, wherein the endoluminal prosthesis further comprises one or more stents supporting the main body graft.

31. The system of claim 28, wherein the main body graft comprises an enlarged portion with an enlarged diameter relative to a remaining portion of the main body graft.

32. The system of claim 28, wherein the delivery catheter comprises a distal tip comprising a plurality of channels, each of the plurality of channels configured to receive a corresponding guidewire sheath.

33. The system of claim 28, wherein the delivery catheter further comprises a plurality of openings in a wall portion of the flexible catheter body.

34. The system of claim 33, wherein each of the plurality of guidewire sheaths is positioned through a corresponding opening in the wall portion of the flexible catheter body.

35. An endoluminal prosthesis system comprising:

a delivery catheter having a flexible catheter body and a proximal and a distal end;

an endoluminal prosthesis comprising a main graft body having a lumen axially therethrough and a plurality of fenestrations in a wall portion of the main graft body, the plurality of fenestrations being in communication with the lumen, the plurality of fenestrations being offset from each other along a length of the main body graft; and

a plurality of pre-loaded guidewires, each of the plurality of guidewires being positioned through at least a portion of the lumen of the main graft body, and through a corresponding fenestration in the wall portion of the main graft body when the endoluminal prosthesis is in a collapsed, pre-delivery state within the catheter body.

36. The system of claim 35, wherein the plurality of fenestrations are longitudinally aligned.

37. The system of claim 35, wherein the plurality of fenestrations comprises a first fenestration, a second fenestration, and a third fenestration.

38. The system of claim 35, wherein the endoluminal prosthesis further comprises one or more stents supporting the main body graft.

39. The system of claim 35, wherein the main body graft comprises an enlarged portion with an enlarged diameter relative to a remaining portion of the main body graft.

40. The system of claim 35, wherein the delivery catheter further comprises a plurality of openings in a wall portion of the flexible catheter body.

41. The system of claim 40, wherein each of the plurality of guidewires is positioned through a corresponding opening in the wall portion of the flexible catheter body.

42. A method of delivering an endoluminal prosthesis, the method comprising:

advancing each of a plurality of guidewires into a corresponding branch of a branched artery; and

advancing an endolouminal prosthesis system over the plurality of guidewires, the endoluminal prosthesis system comprising;

a delivery catheter having a flexible catheter body and a proximal and a distal end;

the endoluminal prosthesis comprising a main graft body having a lumen axially therethrough and a plurality of fenestrations in a wall portion of the main graft body, the plurality of fenestrations being in communication with the lumen, the plurality of fenestrations being offset from each other along a length of the main body graft; and

a plurality of guidewire sheaths, each of the plurality of guidewire sheaths being positioned through at least a portion of the lumen of the main graft body, and through a corresponding fenestration in the wall portion of the main graft body when the endoluminal prosthesis is in a collapsed, pre-delivery state within the catheter body;

wherein advancing the endoluminal prosthesis system comprising advancing the plurality of guidewire sheaths over the plurality of guidewires.

43. The method of claim 42, further comprising advancing each of the plurality of guidewire sheaths into the corresponding branch of the branched artery.

44. The method of claim 43, further comprising advancing a branch stent through each of the plurality of guidewire sheaths.

45. The method of claim 42, further comprising deploying the main body graft by retracting the delivery catheter.

46. The method of claim 45, further comprising advancing each of the plurality of guidewire sheaths into the corresponding branch of the branched artery as main body graft is being deployed.