CONTINUOUS ANALYTE MONITORING SYSTEM

• US 20150182115A1
• Filed: 12/23/2014
• Published: 07/02/2015
• Est. Priority Date: 12/31/2013
• Status: Active Grant

• Current Assignee: Senseonics, Incorporated (Senseonics Holdings, Inc.)
• Original Assignee: Senseonics, Incorporated (Senseonics Holdings, Inc.)
• Inventors: DeHennis, Andrew
• Granted Patent: US 9,814,389 B2
• Time in Patent Office: Days
• US Class Current: 1/1
• CPC Class Codes: A61B 2560/0209 adapted for power saving
• CPC Class Codes: A61B 2560/0219 of externally powered implanted units
• CPC Class Codes: A61B 5/002 Monitoring the patient using a local or closed circuit, e.g. in a room or building A61B5/0017 takes precedence
• CPC Class Codes: A61B 5/0022 Monitoring a patient using a global network, e.g. telephone networks, internet
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/1459 invasive, e.g. introduced into the body by a catheter A61B5/1464 takes precedence
• CPC Class Codes: A61B 5/7275 Determining trends in physiological measurement data; Predicting development of a medical condition based on physiological measurements, e.g. determining a risk factor
• CPC Class Codes: A61B 5/74 Details of notification to user or communication with user or patient indicating measured values G01D7/00; user input means input or output arrangements for computers G06F3/00
• CPC Class Codes: A61B 5/7455 characterised by tactile indication, e.g. vibration or electrical stimulation
• CPC Class Codes: G16H 40/63 for local operation
• CPC Class Codes: G16Z 99/00 Subject matter not provided for in other main groups of this subclass

Abstract

An improved analyte monitoring system having a sensor and a transceiver with improved communication and/or user interface capabilities. The transceiver may communicate with and power the sensor. The transceiver may receive one or more analyte measurements from the sensor and may calculate one or more analyte concentrations based on the received analyte measurements. The transceiver may generate analyte concentration trends, alerts, and/or alarms based on the calculated analyte concentrations. The system may also include a display device, which may be, for example, a smartphone and may be used to display analyte measurements received from the transceiver. The display device may execute a mobile medical application. The system may include a data management system, which may be web-based.

Claims

1. A system for detecting an amount or concentration of an analyte in vivo within a living organism, the system comprising:

an analyte sensor;

a transceiver configured to receive data signals from the analyte sensor and convey analyte information;

a display device configured to receive analyte information and execute a mobile medical application that displays analyte concentrations.

2. The system of claim 1, wherein the transceiver is configured to calculate an analyte concentration based on the received data signals, and the analyte information conveyed to the display device comprises the calculated analyte concentrations.

3. The system of claim 1, wherein the analyte information conveyed to the display device comprises the received data signals, and the mobile medical application is configured to calculate analyte concentration.

4. A system for detecting an amount or concentration of an analyte in vivo within a living organism, the system comprising:

(A) an analyte sensor comprising;

(A1) an analyte indicator configured to exhibit a detectable property based on the amount or concentration of the analyte in proximity to the analyte indicator;

(A2) sensor elements configured to generate a data signal based on the detectable property exhibited by the analyte indicator; and

(A3) a transceiver interface device configured to receive a power signal and generate power for powering the sensor elements and to convey data signals generated by the sensor elements; and

(B) a transceiver comprising;

(B1) a sensor interface device configured to convey the power signal to the transceiver interface device of the analyte sensor and to receive data signals conveyed by the transceiver interface device of the analyte sensor.

5. The system of claim 4, wherein the analyte sensor is an implantable sensor.

6. The system of claim 4, wherein the transceiver further comprises a processor configured to calculate analyte concentrations based on the received data signals.

7. The system of claim 6, wherein the transceiver further comprises a display interface device configured to convey the calculated analyte concentrations to a display device.

8. The system of claim 7, further comprising a display device configured to receive the analyte concentrations conveyed by the display interface device of the transceiver and to display the received analyte concentrations.

9. The system of claim 8, wherein the display device is a smartphone.

10. The system of claim 8, wherein the display interface of the transceiver comprises a wireless communication circuit configured to wirelessly convey the calculated analyte concentrations to the display device.

11. The system of claim 10, wherein the wireless communication circuit employs a wireless communication standard to wirelessly convey the calculated analyte concentrations.

12. The system of claim 11, wherein the wireless communication standard is a Bluetooth standard.

13. The system of claim 10, wherein the processor of the transceiver is further configured to calculate analyte concentration trends based on the calculated analyte concentrations and to generate alerts or alarms based on the calculated analyte concentrations, and the wireless communication circuit is further configured to wirelessly convey the calculated analyte concentration trends and the generated alerts or alarms to the display device.

14. The system of claim 8, wherein the transceiver does not display the calculated analyte concentrations.

15. The system of claim 8, wherein the display device is configured to upload the received analyte concentrations to a web-based data management system.

16. The system of claim 15, further comprising the web-based data management system.

17. The system of claim 8, wherein the processor of the transceiver is configured to perform an analyte concentration calibration based on one or more user-entered calibration points.

18. The system of claim 17, wherein the display interface device of the transceiver receives the one or more user-entered calibration points from the display device.

19. The system of claim 18, wherein the display device is configured to facilitate user entry of the calibration points.

20. The system of claim 4, wherein the transceiver further comprises a display interface device configured to convey the received data signals to a display device.

21. The system of claim 20, further comprising a display device configured to receive the data signals conveyed by the display interface device of the transceiver, to calculate analyte concentrations based on the received data signals, and to display the calculated analyte concentrations.

22. The system of claim 21, wherein the display device is further configured to calculate analyte concentration trends based on the calculated analyte concentrations and to generate alerts or alarms based on the calculated analyte concentrations.

23. The system of claim 21, wherein the display device is a smartphone.

24. The system of claim 21, wherein the display device is configured to upload the calculated analyte concentrations to a web-based data management system.

25. The system of claim 24, further comprising the web-based data management system.

26. The system of claim 8, wherein the display device is configured to perform an analyte concentration calibration based on one or more user-entered calibration points.

27. The system of claim 26, wherein the display device is configured to facilitate user entry of the calibration points.

28. The system of claim 4, wherein the analyte sensor further comprises a sensor housing, and the sensor elements and transceiver interface device are contained within the sensor housing.

29. The system of claim 4, wherein the detectable property is an optical property.

30. The system of claim 4, wherein the sensor elements comprise a light source and a photodetector.

31. The system of claim 4, wherein the analyte is glucose.

32. The system of claim 4, wherein the transceiver interface device of the analyte sensor is an antenna configured to wirelessly receive the power signal from the transceiver and to wirelessly convey the data signals generated by the sensor elements, and the sensor interface device of the transceiver is an antenna configured to wirelessly convey the power signal to the antenna of the analyte sensor and to receive the data signals from the antenna of the analyte sensor.

33. The system of claim 32, wherein the antennas of the analyte sensor and transceiver are inductive elements.

34. The system of claim 4, wherein the sensor interface device of the transceiver and the transceiver interface device of the analyte sensor are a wire connected through a transdermal needle tip.

35. The system of claim 4, wherein the transceiver is external.

36. The system of claim 4, wherein the transceiver is internal.

37. The system of claim 8, wherein the transceiver does display the calculated analyte concentrations.

38. The system of claim 37, wherein the transceiver displays the calculated analyte concentrations via an LCD or LED.

39. A transceiver comprising:

a sensor interface device configured to convey a power signal to an analyte sensor and to receive data signals conveyed by the analyte sensor; and

a display interface device configured to convey the calculated analyte information to a display device.

40. The transceiver of claim 39, further comprising a processor configured to calculate analyte concentrations based on the received data signals;

wherein the analyte information conveyed to the display device by the display interface device comprises the calculated analyte concentrations.

41. The transceiver of claim 39, wherein the analyte information conveyed to the display device by the display interface device comprises the received data signals.

42. The transceiver of claim 39, further comprising an accelerometer.

43. The transceiver of claim 39, further comprising a global positioning unit.