SYSTEM AND METHOD FOR DYNAMICALLY CALIBRATING AND MEASURING ANALYTE CONCENTRATION IN DIABETES MANAGEMENT MONITORS
First Claim
Patent Images
1. An optical analyte sensor for determining a concentration of an analyte, comprising:
- a matrix for receiving a sample containing the analyte at an unknown concentration;
a light emitter for emitting light at a stimulation frequency upon the sample;
a light receiver for receiving a fluorescence signal at a first isosbestic frequency, and at a second frequency, and for measuring an intensity of the fluorescence signal at the first and second frequencies;
a processor for determining a concentration of the analyte based on the respective intensities measured at the first and second frequencies.
5 Assignments
0 Petitions
Accused Products
Abstract
An optical analyte sensor and diabetes management system is provided. The sensor preferably includes a hydrogel matrix for receiving a sample containing an analyte at unknown concentration, a light emitter for emitting light at a stimulation frequency, a light receiver for receiving a fluorescence signal at a first isosbestic frequency, and at a second frequency, for measuring an intensity of the fluorescence signal and the first and second frequencies. A processor determines a concentration of the analyte based on the respective intensities.
15 Citations
30 Claims
-
1. An optical analyte sensor for determining a concentration of an analyte, comprising:
-
a matrix for receiving a sample containing the analyte at an unknown concentration; a light emitter for emitting light at a stimulation frequency upon the sample; a light receiver for receiving a fluorescence signal at a first isosbestic frequency, and at a second frequency, and for measuring an intensity of the fluorescence signal at the first and second frequencies; a processor for determining a concentration of the analyte based on the respective intensities measured at the first and second frequencies. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
-
-
12. A diabetes management system comprising an optical analyte sensor and an insulin infusion device, wherein the optical analyte sensor comprises:
-
a matrix for receiving a sample containing the analyte at an unknown concentration; a light emitter for emitting light at a stimulation frequency upon the sample; a light receiver for receiving a fluorescence signal at a first isosbestic frequency, and at a second frequency, and for measuring an intensity of the fluorescence signal at the first and second frequencies; a processor for determining a concentration of the analyte based on the respective intensities measured at the first and second frequencies; and wherein the analyte sensor further comprises a transceiver for transmitting a signal to the insulin infusion device. - View Dependent Claims (13, 14, 15, 16, 17, 18, 19)
-
-
20. An optical analyte sensor comprising:
-
a matrix for receiving a sample containing the analyte at an unknown concentration; a light emitter for emitting light at a stimulation frequency upon the sample; a light receiver for receiving a fluorescence signal at a first isosbestic frequency, and at a second frequency, and for measuring an intensity of the fluorescence signal at the first and second frequencies; a processor for determining a concentration of the analyte based on the respective intensities measured at the first and second frequencies;
wherein said processor further determines a sensor drift based on previous intensity measurements and corrects the determined concentration based on the determined sensor drift. - View Dependent Claims (21, 22, 23, 24, 25, 26, 27, 28, 29, 30)
-
Specification