Transdermal Porator and Patch System and Method for Using Same

• US 20150190074A1
• Filed: 01/03/2014
• Published: 07/09/2015
• Est. Priority Date: 03/11/2002
• Status: Active Grant

• Current Assignee: ​Passport Technologies, Inc.
• Original Assignee: Nitto Denko Corporation
• Inventors: McRae, Stuart
• Granted Patent: US 9,918,665 B2
• Time in Patent Office: Days
• US Class Current: 1/1
• CPC Class Codes: A61B 5/14503 invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors A61B5/1459, A61B5/1464, A61B5/1473, A61B5/1482, A61B5/14865 take precedence
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/15 Devices for taking samples of blood hypodermic syringes A61M5/178
• CPC Class Codes: A61B 5/685 Microneedles
• CPC Class Codes: A61M 2037/0007 having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
• CPC Class Codes: A61N 1/0428 Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
• CPC Class Codes: A61N 1/303 Constructional details electrodes for external use A61N1/0428
• CPC Class Codes: A61N 1/327 for enhancing the absorption properties of tissue, e.g. by electroporation

Abstract

A transdermal permeant delivery of at least one permeant composition into a tissue membrane of a subject including a disposable substate having at least a portion of a bottom surface of a first release liner connected to an upper surface of the substrate and a patch having a backing layer and a reservoir that is selectively removable from the top surface of the first release liner. In a connected position, a first portion of the backing layer of the patch is releaseably mounted to a top surface of the first release liner in spaced registration with a poration area of the substate.

Claims

1. A method of transdermal monitoring, comprising steps of:

forming at least one micropore in a biological membrane; and

monitoring a subcutaneous fluid via the at least one micropore.

2. A transdermal monitoring system, comprising:

a microporation device adapted to form at least one micropore in a biological membrane; and

a monitoring device adapted to monitor a subcutaneous fluid via the at least one micropore.