CARBON NANOSTRUCTURE SENSOR AND METHOD FOR BIOMOLECULE SENSING
First Claim
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1. A device for measuring a biological target species in a fluid comprising:
- a reference electrode in communication with a fluid;
a sensing electrode in communication with the fluid and disposed between a first electrical contact and a second electrical contact;
wherein the sensing electrode includes one or more carbon nanostructures functionalized with a chemically stable moiety that responds to a biological target species in the fluid when a potential is applied across the first and second electrical contacts to provide a current correlating to a concentration of the target species in the fluid.
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Abstract
Carbon nanostructures may be protected and functionalized using a layer-by-layer method whereby functional groups on the carbon nanostructure surface may be further derivatized to incorporate additional functional moieties. Carbon nanostructures functionalized using such a layer-by-layer method may be used to disperse, sort, separate and purify carbon nanostructures and may be used as sensing elements such as voltametric, amperometric, and potentiometric pH sensors or as biosensors, biometric sensing elements and electrodes and intracorporeal sensors and electrodes.
4 Citations
28 Claims
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1. A device for measuring a biological target species in a fluid comprising:
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a reference electrode in communication with a fluid; a sensing electrode in communication with the fluid and disposed between a first electrical contact and a second electrical contact; wherein the sensing electrode includes one or more carbon nanostructures functionalized with a chemically stable moiety that responds to a biological target species in the fluid when a potential is applied across the first and second electrical contacts to provide a current correlating to a concentration of the target species in the fluid. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A method for measuring a biological target species in a fluid comprising the steps of:
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providing a sensor, the sensor having a reference electrode and a sensing electrode, the sensing electrode disposed between a first contact and a second contact; applying a potential across the reference and sensing electrodes; measuring current resulting from the applied potential; and determining a concentration of a biological target species in the fluid as a function of the measured current. - View Dependent Claims (13, 14, 15, 16, 17, 18, 19, 20)
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21. A system for measuring a concentration of a biological target species in a fluid comprising:
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a sensor for measuring a concentration of a biological target species in a fluid having; a reference electrode in communication with the fluid, and a sensing electrode in communication with the fluid and disposed between a first electrical contact and a second electrical contact, wherein the sensing electrode includes one or more carbon nanostructures functionalized with a chemically stable moiety that responds to a biological target species in the fluid when a potential is applied across the first and second electrical contacts; circuitry for measuring a current resulting from the applied potential and for providing an output signal, the measured current correlating to the concentration of the biological target species in the fluid; and a transmitter for transmitting the output signal to a location remote from the sensor. - View Dependent Claims (22, 23, 24, 25, 26, 27, 28)
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Specification