MITRAL VALVE INVERSION PROSTHESES

• US 20150238312A1
• Filed: 09/13/2013
• Published: 08/27/2015
• Est. Priority Date: 09/14/2012
• Status: Active Grant

• Current Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Original Assignee: Millepede, LLC
• Inventors: Lashinski, Randall
• Granted Patent: US 9,610,156 B2
• Time in Patent Office: Days
• US Class Current: 1/1
• CPC Class Codes: A61F 2/2409 Support rings therefor, e.g. for connecting valves to tissue annuloplasty rings A61F2/2442
• CPC Class Codes: A61F 2/2436 Deployment by retracting a sheath
• CPC Class Codes: A61F 2/2442 Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
• CPC Class Codes: A61F 2/2445 Annuloplasty rings in direct contact with the valve annulus
• CPC Class Codes: A61F 2/2457 Chordae tendineae prostheses
• CPC Class Codes: A61F 2/2466 Delivery devices therefor
• CPC Class Codes: A61F 2/2487 Devices within the heart chamber, e.g. splints
• CPC Class Codes: A61F 2220/0016 with sharp anchoring protrusions, e.g. barbs, pins, spikes
• CPC Class Codes: A61F 2250/001 for adjusting a diameter
• CPC Class Codes: A61H 23/00 Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms apparatus for passive exercising A61H1/00; generating or transmitting mechanical vibrations in general B06B

Abstract

The present disclosure includes a method comprising inserting an implant proximate a mitral valve, the implant comprising a tubular body and a plurality of piercing members, the tubular body comprising an upper diameter and a lower diameter. The method also includes engaging tissue proximate the mitral valve by the plurality of piercing members and transitioning the tubular body from a first structural configuration to a second structural configuration by application of an expansive force to the tubular body proximate the upper diameter, the first structural configuration having the upper diameter smaller than the lower diameter and the second structural configuration having the upper diameter larger than the lower diameter. The present disclosure also includes associated systems and implants.

Claims

1. A method comprising:

inserting an implant proximate a mitral valve, the implant comprising a tubular body and a plurality of piercing members, the tubular body comprising an upper diameter and a lower diameter;

engaging tissue proximate the mitral valve by the plurality of piercing members; and

transitioning the tubular body from a first structural configuration to a second structural configuration by application of an expansive force to the tubular body proximate the upper diameter, the first structural configuration having the upper diameter smaller than the lower diameter and the second structural configuration having the upper diameter larger than the lower diameter.

2. The method of claim 1, engaging tissue proximate the mitral valve by the plurality of piercing members further comprising applying vibration to at least one of the plurality of piercing members.

3. The method of claim 1, engaging tissue proximate the mitral valve by the plurality of piercing members further comprising applying vibration to the tissue proximate the mitral valve either on a same side of the mitral valve as the implant or on a side of the mitral valve opposite the implant.

4. The method of claim 1, transitioning the tubular body further comprising applying an upward force on a fixed ring positioned within the tubular body, the fixed ring comprising a diameter larger than the upper diameter in the first structural configuration.

5. The method of claim 1, transitioning the tubular body further comprising:

placing an expandable ring proximate the upper diameter; and

expanding the expandable ring to increase the upper diameter.

6. The method of claim 1, wherein at least one of the plurality of piercing members is covered during the insertion of the implant proximate the mitral valve.

7. The method of claim 1, engaging tissue proximate the mitral valve by the plurality of piercing members further comprising at least one of the plurality of piercing members coupling with a location ring positioned on a side of the mitral valve opposite the implant.

8. The method of claim 1, wherein at least one of the plurality of piercing members engages the tissue proximate the mitral valve before another of the plurality of piercing members.

9. An implant comprising:

a tubular body comprising an upper diameter and a lower diameter, the tubular body having a first structural configuration in which the upper diameter is smaller than the lower diameter and a second structural configuration in which the upper diameter is larger than the lower diameter, the tubular body configured to transition from the first structural configuration to the second structural configuration by application of an expansive force to the tubular body proximate the upper diameter; and

a plurality of piercing members connected to the tubular body and proximate the lower diameter to engage tissue proximate a mitral valve.

10. The implant of claim 9, further comprising a vibration pad for applying vibration to at least one of the plurality of piercing members.

11. The implant of claim 9 further comprising a fixed ring positioned within the tubular body, the fixed ring comprising a diameter larger than the upper diameter in the first structural configuration such that when the fixed ring is moved proximate the upper diameter, the implant transitions from the first structural configuration to the second structural configuration.

12. The implant of claim 9, further comprising an expandable ring proximate the upper diameter, the expandable ring configured to increase the upper diameter of the implant when the expandable ring is expanded.

13. The implant of claim 9, further comprising a temporary covering for at least one of the plurality of piercing members.

14. The implant of claim 9, wherein the plurality of piercing members are integrally formed with the implant.

15. The implant of claim 9, wherein a wall of the tubular body acts as a beam in deflection when transitioning from the first structural configuration to the second structural configuration.

16. The implant of claim 9, further comprising a third compressed structural configuration for delivery of the implant by one of a trans-septal delivery, trans-apical delivery, or trans-atrial delivery.

17. The implant of claim 9, wherein the upper diameter is approximately twenty five millimeters in the first structural configuration and approximately thirty five millimeters in the second structural configuration.

18. The implant of claim 9, the tubular body having a flat portion oriented toward an aortic valve and a circular portion oriented toward a posterior leaflet of the mitral valve.

19. A system comprising:

a guide wire;

a sheath for sliding over the guide wire;

an implant for delivery to a body by traveling through the sheath and along the guide wire, the implant comprising;

a tubular body comprising an upper diameter and a lower diameter, the tubular body having a first structural configuration in which the upper diameter is smaller than the lower diameter and a second structural configuration in which the upper diameter is larger than the lower diameter, the tubular body configured to transition from the first structural configuration to the second structural configuration by application of an expansive force to the tubular body proximate the upper diameter; and

a plurality of barbs connected to the tubular body and proximate the lower diameter to penetrate tissue proximate a mitral valve.

20. The system of claim 19, further comprising a location ring located on a side of the mitral valve opposite the implant and coupled with the implant.