TRANSCATHETER MITRAL VALVE STENT FRAMES

• US 20150272737A1
• Filed: 03/19/2015
• Published: 10/01/2015
• Est. Priority Date: 03/26/2014
• Status: Abandoned Application

• Current Assignee: St. Jude Medical Cardiology Division Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: St. Jude Medical Cardiology Division Incorporated (Abbott Laboratories Incorporated)
• Inventors: Dale, Theodore Paul, Benson, Thomas Mark, Para, Andrea N., Satam, Gaurav, Diedering, Jason, Kumar, Saravana B.
• Application Number:
  US14/662,464
• Publication Number:
  US 20150272737A1
• Time in Patent Office: Days
• US Class Current: 1/1
• CPC Class Codes: A61F 2/2409 Support rings therefor, e.g. for connecting valves to tissue annuloplasty rings A61F2/2442
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2/2442 Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
• CPC Class Codes: A61F 2/2445 Annuloplasty rings in direct contact with the valve annulus
• CPC Class Codes: A61F 2220/0008 Fixation appliances for connecting prostheses to the body
• CPC Class Codes: A61F 2220/0016 with sharp anchoring protrusions, e.g. barbs, pins, spikes
• CPC Class Codes: A61F 2230/0065 toroidal, e.g. ring-shaped, doughnut-shaped
• CPC Class Codes: A61F 2230/0069 cylindrical

Abstract

A prosthetic heart valve may include a stent having an inflow end, an outflow end, a collapsed condition, and an expanded condition. The prosthetic valve may also include a collapsible and expandable valve assembly disposed within the stent and having a plurality of leaflets. The prosthetic valve and/or stent may include features to anchor the prosthetic valve to a native valve annulus and to seal the prosthetic valve with respect to the native valve annulus, such as planar and/or nonplanar annular sealing members coupled to ends of the stent. The stent may include one or more circumferential rows of anchor members or hooks extending radially outwardly from the stent. These hooks may be configured to extend in a particular direction when the stent is in the collapsed condition to facilitate resheathing of the stent if, upon deployment, a user determines the prosthetic heart valve is not positioned optimally.

Claims

1. A prosthetic heart valve, comprising:

a stent having an inflow end, an outflow end, a center portion between the inflow end and the outflow end, a collapsed condition, and an expanded condition;

a collapsible and expandable valve assembly disposed within the stent and having a plurality of leaflets;

a first annular sealing member coupled to the inflow end; and

a second annular sealing member coupled to the outflow end.

2. The prosthetic heart valve of claim 1, wherein the first and second sealing members each have a diameter greater than a diameter of the stent when the stent is in the expanded condition.

3. The prosthetic heart valve of claim 2, wherein the stent is substantially cylindrical in the expanded condition.

4. The prosthetic heart valve of claim 2, wherein the first sealing member has a substantially planar configuration when the stent is in the expanded condition.

5. The prosthetic heart valve of claim 2, wherein the inflow end and the outflow end of the stent each has a diameter greater than a diameter of the center portion of the stent when the stent is in the expanded condition.

6. The prosthetic heart valve of claim 2, wherein the first sealing member is substantially nonplanar when the stent is in the expanded condition.

7. The prosthetic heart valve of claim 6, wherein an outer perimeter of the first sealing member is closer to the outflow end than an inner perimeter of the first sealing member when the stent is in the expanded condition.

8. The prosthetic heart valve of claim 6, wherein an outer perimeter of the second sealing member is closer to the inflow end than an inner perimeter of the second sealing member when the stent is in the expanded condition.

9. A stent having an expanded condition and a collapsed condition, comprising:

a substantially cylindrical body having a first end and a second end;

a flared portion coupled to the first end of the body and extending radially outwardly from the body and away from the second end of the body when the stent is in the expanded condition; and

a plurality of anchor members each having a first end coupled to the body and a second free end extending radially outwardly from the body and toward the first end of the body when the stent is in the expanded condition,

wherein the flared portion and the second free ends of the anchor members are configured to extend away from the second end of the body when the stent is in the collapsed condition.

10. The stent of claim 9, wherein the flared portion and the body are each formed of a plurality of struts that form cells having an area, the area of each cell of the body being greater than the area of each cell of the flared portion when the stent is in the expanded condition.

11. The stent of claim 9, wherein the flared portion and the body are each formed of a plurality of struts having a thickness, the thickness of the struts forming the flared portion being less than the thickness of the struts forming the body.

12. A stent having an expanded condition and a collapsed condition, comprising:

a substantially cylindrical center body having a first end and a second end;

a first plurality of anchor members each having a first end coupled to the first end of the body and a second free end extending radially outwardly from the body and toward the second end of the body when the stent is in the expanded condition; and

a second plurality of anchor members each having a first end coupled to the body and a second free end extending radially outwardly from the body and toward the second end of the body when the stent is in the expanded condition,

wherein the first and second plurality of anchor members are configured to extend toward the second end of the body when the stent is in the collapsed condition.

13. A stent having an expanded condition and a collapsed condition, comprising:

a substantially cylindrical center body having a first end and a second end;

a first plurality of anchor members each having a first end coupled to the body and a second free end extending radially outwardly from the body and toward the first end of the body when the stent is in the expanded condition; and

a second plurality of anchor members each having a first end coupled to the first end of the body and a second free end extending radially outwardly from the body and toward the second end of the body when the stent is in the expanded condition,

wherein the first plurality of anchor members extend toward the first end of the body and the second plurality of anchor members extend toward the second end of the body when the stent is in the collapsed condition.

14. The stent of claim 13, wherein the second plurality of anchor members includes a first group of anchor members and a second group of anchor members, the first group being configured to engage a native posterior mitral valve leaflet and the second group being configured to engage a native anterior mitral valve leaflet when the stent is implanted in a native mitral valve annulus of a patient.

15. A stent having an expanded condition and a collapsed condition, comprising:

a substantially cylindrical center body having a first end, a second end, and a longitudinal axis extending between the first end and the second end;

a first plurality of anchor members each having a first end coupled to the body and a second free end extending radially outwardly from the body and substantially perpendicular to the longitudinal axis of the body when the stent is in the expanded condition; and

a second plurality of anchor members each having a first end coupled to the body and a second free end extending radially outwardly from the body and substantially perpendicular to the longitudinal axis of the body when the stent is in the expanded condition,

wherein the first plurality of anchor members extend away from the second end of the body and the second plurality of anchor members extend away from the first end of the body when the stent is in the collapsed condition.

16. The stent of claim 15, further comprising:

a plurality of struts forming a first circumferential row of cells and a second circumferential row of cells,

wherein each of the first plurality of anchor members is at least partially formed from one of the cells in the first circumferential row and each of the second plurality of anchor members is at least partially formed from one of the cells in the second circumferential row.

17. A prosthetic heart valve, comprising:

a stent having an inflow end, an outflow end, a collapsed condition, and an expanded condition, the stent being formed from wire and having a first series of hooks and a second series of hooks; and

a cuff coupled to the stent,

wherein, when the stent is in the expanded condition, each hook of the first series extends radially outwardly from the stent at the inflow end and each hook of the second series includes a first portion that extends radially outwardly from the stent at the outflow end and a second portion that extends toward the inflow end.

18. The prosthetic heart valve of claim 17, wherein the cuff has a first substantially flat portion that spans across and is coupled to the first series of hooks.

19. A prosthetic heart valve, comprising:

a stent having an inflow end, an outflow end, a collapsed condition, and an expanded condition, the stent being formed of a plurality of struts;

a collapsible and expandable valve assembly disposed within the stent and having a plurality of leaflets; and

a commissure attachment feature attached to at least one of the plurality of struts and positioned between the inflow end and the outflow end when the stent is in the expanded condition.

20. The prosthetic heart valve of claim 19, wherein the commissure attachment feature has a first end attached to at least one of the plurality of struts and a second free end extending toward the inflow end when the stent is in the expanded condition.