PHARMACEUTICAL COMPOSITIONS
3 Assignments
0 Petitions
Accused Products
Abstract
Methods and compositions are provided which comprise effective amounts of analgesic to treat a subject, including reducing or eliminating an adverse effect associated with the analgesic.
17 Citations
162 Claims
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1-138. -138. (canceled)
- 139. A solid composition, comprising an immediate-release layer that comprises an antiemetic, and a controlled-release layer that comprises an opioid analgesic and a non-opioid analgesic, wherein about 90% of the antiemetic is released in about 1 minute to about 20 minutes following contact of the solid composition with a dissolution fluid as measured by USP Apparatus 2 (Paddle Apparatus), and wherein 30-60% of the opioid analgesic is released in 5 to 10 minutes following contact of the solid composition with a dissolution fluid as measured by USP Apparatus 2 (Paddle Apparatus).
Specification