EXPANDABLE IMPLANT DEVICES FOR FILTERING BLOOD FLOW FROM ATRIAL APPENDAGES

• US 20160008122A1
• Filed: 09/25/2015
• Published: 01/14/2016
• Est. Priority Date: 08/18/2000
• Status: Active Application

• Current Assignee: Atritech Inc. (Boston Scientific Corporation)
• Original Assignee: Atritech Inc. (Boston Scientific Corporation)
• Inventors: Borillo, Thomas E., Peterson, Dean, Sutton, Gregg S., Welch, Jeffrey
• Granted Patent: US 10,278,805 B2
• Time in Patent Office: Days
• US Class Current: 1/1
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12122 within the heart for closing a cardiac septal defect A61B17/0057
• CPC Class Codes: A61B 17/12136 Balloons
• CPC Class Codes: A61B 17/12159 Solid plugs; being solid before insertion
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 2017/00575 for closure at remote site, e.g. closing atrial septum defects
• CPC Class Codes: A61F 2/013 Distal protection devices, i.e. devices placed distally in combination with another endovascular procedure, e.g. angioplasty or stenting
• CPC Class Codes: A61F 2002/015 Stop means therefor
• CPC Class Codes: A61F 2002/016 made from wire-like elements
• CPC Class Codes: A61F 2002/018 made from tubes or sheets of material, e.g. by etching or laser-cutting
• CPC Class Codes: A61F 2230/0006 circular
• CPC Class Codes: A61F 2230/0069 cylindrical
• CPC Class Codes: A61F 2230/008 paraboloidal

Abstract

Implant devices for filtering blood flowing through the ostium of an atrial appendage have component structures one or more of which are expandable. Devices with component structures in their unexpanded state have a compact size suitable for intra-cutaneous delivery to an atrial appendage situs. The expandable component structures are expanded in situ to deploy the devices. A device may have sufficiently short axial length so that most or almost all of the device length may fit within the ostium region.

Claims

1. An expandable structure deployable within an ostium of an atrium comprising:

an expandable stent having a first end, a second end, a radially compact delivery configuration, a generally cylindrical expanded configuration defining a longitudinal axis in which the expandable stent has an expanded radial dimension greater than a radially compact dimension of the delivery configuration and an expanded length greater than the length of the ostium within which the expandable structure is to be deployed;

the first end having a self-sealing opening formed by overlapping membrane flaps sized and adapted to cover the ostium.

2. The expandable structure of claim 1, wherein the expandable stent is self-expanding.

3. The self-expanding expandable stent of claim 2, wherein the expansion mechanism is formed from shape memory alloy components.

4. The self-expanding expandable stent of claim 2, wherein the expansion mechanism is formed from springs or elastic components.

5. The expandable structure of claim 1, wherein a removable component expands the expandable stent.

6. The expandable structure of claim 5, wherein the removable component is a balloon.

7. The expandable structure of claim 1, further comprising a tubular membrane disposed outside of the expandable stent.

8. The expandable structure of claim 7, wherein the tubular membrane is made from biocompatible materials.

9. The expandable structure of claim 8, wherein the biocompatible materials include ePTFE.

10. The expandable structure of claim 7, wherein the expandable stent provides outward pressure adapted to reduce flow leakage about the periphery of the expandable structure.

11. The expandable structure of claim 1, further comprising an anterior portion and a posterior portion.

12. The expandable structure of claim 11, wherein the posterior portion is formed of a wire mesh or a braided or woven fabric.

13. The expandable structure of claim 11, wherein the posterior portion is flared with its diameter increasing along its axial length.

14. The expandable structure of claim 11, wherein the posterior portion has barbs distributed over at least a part of its exterior surface area.

15. The expandable structure of claim 14, wherein the barbs engage surrounding ostium walls to secure the device in position.

16. A method of implanting an expandable structure within an ostium of an atrium comprising the steps of:

advancing a delivery catheter containing an expandable structure having a first end having a self-sealing opening formed by overlapping membrane flaps sized and adapted to cover the an ostium of an atrium through the vasculature to an atrium of a patient;

positioning the delivery catheter adjacent the ostium within which the expandable structure is to be deployed;

advancing the expandable structure into the ostium in a radially compact delivery configuration;

expanding the expandable structure within the ostium to a generally cylindrical expanded configuration; and

withdrawing the delivery catheter from the patient.

17. The method of claim 16, wherein the expanding step is accomplished with a removable component.

18. The method of claim 16, wherein the expanding step is accomplished with a removable balloon.

19. The method of claim 16, wherein the expandable structure is self-expanding.