COMPOSITION FOR BRAIN ACTIVATION, COMPRISING GINSENG FRUIT EXTRACT

• US 20160051605A1
• Filed: 03/27/2014
• Published: 02/25/2016
• Est. Priority Date: 04/02/2013
• Status: Active Grant

• Current Assignee: Amore Pacific Corporation
• Original Assignee: Amore Pacific Corporation
• Inventors: SHIN, Hyun Jung, PARK, Chan Woong, KIM, Su Hwan, SEO, Dae Bang, KIM, Wan Gi, LEE, Sang Jun
• Granted Patent: US 10,555,983 B2
• Time in Patent Office: Days
• US Class Current: 1/1
• CPC Class Codes: A23L 2/52 Adding ingredients adding preservatives A23L2/44
• CPC Class Codes: A23L 33/105 Plant extracts, their artificial duplicates or their derivatives
• CPC Class Codes: A23V 2002/00 Food compositions, function of food ingredients or processes for food or foodstuffs
• CPC Class Codes: A23V 2200/322 having an effect on the health of the nervous system or on mental function
• CPC Class Codes: A23V 2250/156 Mineral combination undefined extract A23V2250/1638
• CPC Class Codes: A23V 2250/21 Plant extracts
• CPC Class Codes: A23V 2250/702 Vitamin A
• CPC Class Codes: A23V 2250/704 Vitamin B
• CPC Class Codes: A23V 2250/712 Vitamin E
• CPC Class Codes: A61K 31/704 attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin digitoxin A61K31/7048
• CPC Class Codes: A61K 36/258 Panax (ginseng)
• CPC Class Codes: A61P 1/14 Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
• CPC Class Codes: A61P 25/00 Drugs for disorders of the nervous system
• CPC Class Codes: A61P 25/24 Antidepressants
• CPC Class Codes: A61P 25/28 for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
• CPC Class Codes: A61P 39/00 General protective or antinoxious agents
• CPC Class Codes: A61P 9/10 for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

Provided in the present specification is a composition for brain activation, comprising ginseng fruit extract as an active ingredient. The composition according to the present specification allows an increase in blood flow in the brain and thus has an effect of ameliorating chronic fatigue syndrome. In addition, the composition according to the present specification activates the brain, and as a result, strengthens connectivity strength between the frontal lobe and the occipital lobe and thus has an effect of improving problem-solving accuracy and reducing solving time in the area of cognitive ability. Therefore, the composition according to the present specification can be used as a pharmaceutical composition or a food composition for patients suffering from chronic fatigue syndrome.

Claims

1. A method for activating the brain, for improving cognitive function, for improving, treating or suppressing chronic fatigue syndrome, or for improving the symptoms of chronic fatigue syndrome comprising, a ginseng fruit extract to activate the brain, to improve cognitive function, to improve, treat or suppress chronic fatigue syndrome, or to improve the symptoms of chronic fatigue syndrome to a subject in need thereof.

5. The method according to claim 1, wherein the symptom of chronic fatigue syndrome is one or more selected from a group consisting of decreased brain activity, reduced brain blood flow, cognitive function decline, disorder of the central nervous system, concentration deficit, attention deficit and memory deficit, depression, and decreased resistance to stresses.

6. The method according to claim 1, wherein the ginseng fruit extract comprises a protopanaxadiol-based ginsenoside (PD) and a protopanaxatriol-based ginsenoside (PT) at a weight ratio (PD/PT) of 0.1-1.5.

7. The composition according to claim 1, wherein the ginseng fruit extract is comprised in a composition, wherein the ginseng fruit extract is comprised in an amount of 0.01-100 wt % based on the total weight of the composition.

8. The composition according to claim 1, wherein the ginseng fruit extract comprises 20 wt % or more of a crude saponin based on the total weight of the ginseng fruit extract.

9. The composition according to claim 1, wherein the ginseng fruit extract is an extract of water or a C1-C6 lower alcohol.

10. The composition according to claim 1, wherein the ginseng fruit extract comprises 5-30 wt % of ginsenoside Re based on the total weight of the ginseng fruit extract.

11. The composition according to claim 1, wherein the composition is in a form selected from a group consisting of a dust, a granule, a tablet, a soft or hard capsule and a drink.

2-4. -4. (canceled)