RENAL PUMP

• US 20160051741A1
• Filed: 11/03/2015
• Published: 02/25/2016
• Est. Priority Date: 03/13/2013
• Status: Active Grant

• Current Assignee: Magenta Medical Ltd.
• Original Assignee: Magenta Medical Ltd.
• Inventors: SCHWAMMENTHAL, Ehud, TUVAL, Yosi, GLOZMAN, Daniel
• Granted Patent: US 9,913,937 B2
• Time in Patent Office: Days
• US Class Current: 1/1
• CPC Class Codes: A61B 5/02055 Simultaneously evaluating both cardiovascular condition and temperature
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61M 2207/00 Methods of manufacture, assembly or production
• CPC Class Codes: A61M 2210/1082 Kidney
• CPC Class Codes: A61M 2210/12 Blood circulatory system
• CPC Class Codes: A61M 60/13 by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
• CPC Class Codes: A61M 60/135 inside a blood vessel, e.g. using grafting
• CPC Class Codes: A61M 60/148 in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices
• CPC Class Codes: A61M 60/237 the blood flow through the rotating member having mainly axial components, e.g. axial flow pumps
• CPC Class Codes: A61M 60/33 of kidneys
• CPC Class Codes: A61M 60/411 generated by an electromotor
• CPC Class Codes: A61M 60/414 transmitted by a rotating cable, e.g. for blood pumps mounted on a catheter
• CPC Class Codes: A61M 60/422 the force acting on the blood contacting member being electromagnetic, e.g. using canned motor pumps
• CPC Class Codes: A61M 60/523 using blood flow data, e.g. from blood flow transducers
• CPC Class Codes: A61M 60/808 specially adapted for deformable impellers, e.g. expandable impellers
• CPC Class Codes: A61M 60/81 Pump housings
• CPC Class Codes: A61M 60/825 Contact bearings, e.g. ball-and-cup or pivot bearings
• CPC Class Codes: A61M 60/833 Occluders for preventing backflow
• CPC Class Codes: A61M 60/861 Connections or anchorings for connecting or anchoring pumps or pumping devices to parts of the patient's body
• CPC Class Codes: A61M 60/896 having flexible or resilient parts, e.g. flap valves

Abstract

Apparatus and methods are described including identifying a subject as suffering from a condition selected from the group consisting of: cardiac dysfunction, congestive heart failure, reduced renal blood flow, increased renal vascular resistance, arterial hypertension, and kidney dysfunction. In response thereto, blood pressure within a renal vein of the subject is reduced, by placing a blood pump inside the subject'"'"'s renal vein and activating the impeller to pump blood from the renal vein into the subject'"'"'s vena cava. Other applications are also described.

Claims

1. An apparatus, comprising:

an impeller, comprising;

an impeller frame that comprises proximal and distal end portions and a plurality of helical elongate elements that wind from the proximal end portion to the distal end portion; and

a material that is coupled to the helical elongate elements, such that the helical elongate elements with the material coupled thereto define at least one blade of the impeller.

2. The apparatus according to claim 1, wherein the impeller is configured to be placed inside a blood vessel of a subject and to pump blood through the blood vessel by rotating with respect to the blood vessel, the apparatus further comprising a radially expandable cage configured to be disposed between the impeller and an inner wall of the blood vessel and to separate the blood vessel wall from the impeller.

3. The apparatus according to claim 1, wherein the proximal and distal end portions comprises proximal and distal rings.

4. The apparatus according to claim 1, wherein at least one of the proximal or distal end portions defines a notch in an edge thereof, the notch being configured to facilitate coupling of the material to the helical elongate elements.

5. The apparatus according to claim 1, wherein the impeller further comprises sutures tied around the helical elongate elements, the sutures being configured to facilitate coupling of the material to the helical elongate elements.

6. The apparatus according to claim 1, wherein the plurality of helical elongate elements comprises three helical elongate elements that wind from the proximal end portion to the distal end portion.

7. The apparatus according to claim 1, wherein the plurality of helical elongate elements comprises two helical elongate elements that wind from the proximal end portion to the distal end portion.

8. The apparatus according to claim 1, wherein each of the helical elongate elements defines less than half a winding of a helix.

9. The apparatus according to claim 1, wherein:

the helical elongate elements define proximal and distal ends thereof,

the helical elongate elements are configured to support the material between the proximal and distal ends of the helical elongate elements, and

the impeller does not comprise any additional supporting member for supporting the material between the proximal and distal ends of the helical elongate elements.

10. The apparatus according to claim 9, wherein the impeller is configured such that rotational motion is imparted from the proximal end portion of the impeller to the distal end portion of the impeller substantially solely via the helical elongate elements of the impeller.

11. A method, comprising:

manufacturing an impeller by;

cutting a tube such that the cut tube defines a structure having first and second end portions at proximal and distal ends of the structure, the end portions being connected to one another by a plurality of elongate elements;

causing the elongate elements to radially expand and form helical elongate elements, by axially compressing the structure; and

coupling a material to the helical elongate elements, such that the helical elongate elements with the material coupled thereto define at least one blade of the impeller.

12. The method according to claim 11, wherein manufacturing the impeller comprises manufacturing a biocompatible impeller that is configured to be inserted into a blood vessel of a subject.

13. The method according to claim 11, wherein cutting the tube further comprises forming a notch in an edge of at least one of the end portions, the notch being configured to facilitate coupling of the material to the helical elongate elements.

14. The method according to claim 11, further comprising tying sutures around the helical elongate elements, the sutures being configured to facilitate coupling of the material to the helical elongate elements.

15. The method according to claim 11, wherein cutting the tube comprises cutting the tube such that the cut tube defines a structure having first and second end portions at proximal and distal ends of the structure, the end portions being connected to one another by three elongate elements, and wherein causing the elongate elements to radially expand and form helical elongate elements comprises causing the elongate elements to form three helical elongate elements.

16. The method according to claim 11, wherein coupling the material to the helical elongate elements comprises dipping at least a portion of the structure into the material, while the material is in a liquid state thereof, and drying the material, while the material is being supported by the helical elongate elements.

17. The method according to claim 11, wherein cutting the tube comprises cutting the tube such that the cut tube defines a structure having first and second end portions at proximal and distal ends of the structure, the end portions being connected to one another by two elongate elements, and wherein causing the elongate elements to radially expand and form helical elongate elements comprises causing the elongate elements to form two helical elongate elements.

18. The method according to claim 17, wherein causing the elongate elements to form the two helical elongate elements comprises causing the elongate elements to form two helical elongate elements, each of the helical elongate elements defining less than half a winding of a helix.

19. The method according to claim 11, wherein cutting the tube comprises cutting the tube such that the cut tube defines a structure having first and second rings at proximal and distal ends of the structure, and such that first and second ends of each of the elongate elements are disposed at an angle from one another with respect to circumferences of the rings, the angle being greater than 50 degrees.

20. The method according to claim 11, wherein cutting the tube comprises cutting the tube such that the cut tube defines a structure having first and second rings at proximal and distal ends of the structure, and such that first and second ends of each of the elongate elements are disposed at an angle from one another with respect to circumferences of the rings, the angle being less than 180 degrees.

21. The method according to claim 11, wherein coupling the material to the helical elongate elements comprises coupling the material to the elongate elements such that, between the proximal and distal ends of the helical elongate elements, the material is supported by the helical elongate elements, in an absence of any additional supporting member between the proximal and distal ends of the helical elongate elements for supporting the material.

22. The method according to claim 21, wherein coupling the material to the helical elongate elements in the absence of any additional supporting member between the proximal and distal ends of the helical elongate elements for supporting the material comprises configuring the impeller such that rotational motion is imparted from the proximal end portion to the distal end portion substantially solely via the helical elongate elements of the impeller.