METHODS AND COMPOSITIONS FOR PREVENTING OR TREATING OPHTHALMIC CONDITIONS
5 Assignments
0 Petitions
Accused Products
Abstract
The disclosure generally describes methods of preventing or treating ophthalmic diseases or conditions in a mammalian subject, such as diabetic retinopathy, cataracts, retinitis pi gmentosa, glaucoma, macular degeneration, choroidal neovascularization, retinal degeneration, and oxygen-induced retinopathy. The methods comprise administering an effective amount of an aromatic-cationic peptide to subjects in need thereof.
3 Citations
19 Claims
-
1-10. -10. (canceled)
-
11. A method for treating an ophthalmic condition in a subject in need thereof, comprising administering to the subject a peptide represented by the formula D-Arg-2′
- 6′
-Dmt-Lys-Phe-NH2 or Phe-D-Arg-Phe-Lys-NH2, wherein the ophthalmic condition is selected from the group consisting of;
retinal edema and retinal vascular occlusions, and wherein the subject is diagnosed as having or suspected of having said ophthalmic condition. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19)
- 6′
Specification