BONE TREATMENT SYSTEMS AND METHODS
First Claim
1. A bone cement composition configured to provide a controlled viscosity, comprising:
- a liquid component comprising a monomer; and
a non-liquid component comprising first polymer beads having a first average cross-sectional dimension and comprising a radical initiator at a first amount, and second polymer beads having a second average cross-sectional dimension greater than the first average cross-sectional dimension and comprising the radical initiator at a second amount lower than the first amount.
2 Assignments
0 Petitions
Accused Products
Abstract
The present disclosure relates to bone cement formulations that have an extended working time for use in vertebroplasty procedures and other osteoplasty procedures together with cement injectors that include energy delivery systems for on-demand control of cement viscosity and flow parameters. The bone cement formulations may include a liquid component having at least one monomer and a non-liquid component including polymer particles and benzoyl peroxide (BPO). The non-liquid component may be further configured to allow controlled exposure of the BPO to the liquid monomer so as to enable control of the viscosity of the bone cement composition.
3 Citations
20 Claims
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1. A bone cement composition configured to provide a controlled viscosity, comprising:
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a liquid component comprising a monomer; and a non-liquid component comprising first polymer beads having a first average cross-sectional dimension and comprising a radical initiator at a first amount, and second polymer beads having a second average cross-sectional dimension greater than the first average cross-sectional dimension and comprising the radical initiator at a second amount lower than the first amount. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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10. A bone cement composition, comprising:
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a liquid component comprising a monomer; and a non-liquid component comprising a plurality of polymer bead populations having different dissolution rates and different amounts of an initiator, wherein one of the polymer bead populations has a lower dissolution rate and a higher amount of the initiator compared to another one of the polymer bead populations, such that upon forming a mixture with the liquid component, an initiator availability in the mixture increases relatively rapidly during a first time interval and thereafter stays relatively constant during a second time interval compared to the first time interval. - View Dependent Claims (11, 12, 13, 14, 15, 16)
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17. A method of providing a bone cement mixture having a controlled viscosity, the method comprising:
mixing a liquid component comprising a monomer and a non-liquid component comprising at plurality of polymer bead populations having different dissolution rates and different amounts of an initiator, wherein mixing dissolves one of the polymer bead populations having a higher amount of an initiator at a faster rate compared to a dissolution rate another one of the polymer bead populations having a lower amount of the initiator, such that an initiator availability in the mixture initially increases relatively rapidly during a first time interval, followed by a second time interval during which the initiator availability stays substantially constant relative to the first time interval. - View Dependent Claims (18, 19, 20)
Specification