Methods, Systems and Devices for Non-Invasive Open Ventilation for Treating Airway Obstructions

• US 20160095997A1
• Filed: 12/10/2015
• Published: 04/07/2016
• Est. Priority Date: 04/02/2009
• Status: Active Grant

• Current Assignee: Breathe Technologies, Inc. (Baxter International Inc.)
• Original Assignee: Breathe Technologies, Inc. (Baxter International Inc.)
• Inventors: Kapust, Gregory, Allum, Todd, Wondka, Anthony D., Cipollone, Joseph, Gerber, Anthony, Eghbal, Darius, Aguirre, Joey, Kassanis, George A.
• Granted Patent: US 10,232,136 B2
• Time in Patent Office: Days
• US Class Current: 1/1
• CPC Class Codes: A61M 16/0003 Accessories therefor, e.g. sensors, vibrators, negative pressure
• CPC Class Codes: A61M 16/0006 with means for creating vibrations in patients' airways
• CPC Class Codes: A61M 16/0057 Pumps therefor
• CPC Class Codes: A61M 16/0066 Blowers or centrifugal pumps
• CPC Class Codes: A61M 16/0069 the speed thereof being controlled by respiratory parameters, e.g. by inhalation
• CPC Class Codes: A61M 16/0096 High frequency jet ventilation
• CPC Class Codes: A61M 16/0493 with means for protecting the tube from damage caused by the patient's teeth, e.g. bite block
• CPC Class Codes: A61M 16/0605 Means for improving the adaptation of the mask to the patient
• CPC Class Codes: A61M 16/0622 having an underlying cushion
• CPC Class Codes: A61M 16/0666 Nasal cannulas or tubing devices for improving normal breathing through the nose A61F5/08; nose filters A62B23/06; outside holding devices A61M25/02
• CPC Class Codes: A61M 16/0677 Gas-saving devices therefor
• CPC Class Codes: A61M 16/0683 Holding devices therefor
• CPC Class Codes: A61M 16/0688 by means of an adhesive
• CPC Class Codes: A61M 16/0825 with ball-sockets
• CPC Class Codes: A61M 16/0841 for sampling
• CPC Class Codes: A61M 16/0858 Pressure sampling ports
• CPC Class Codes: A61M 16/0875 Connecting tubes
• CPC Class Codes: A61M 16/0883 Circuit type
• CPC Class Codes: A61M 16/101 using an oxygen concentrator
• CPC Class Codes: A61M 16/107 in the inspiratory path
• CPC Class Codes: A61M 16/127 : by Venturi effect, i.e. entrainment mixers
• CPC Class Codes: A61M 16/16 : Devices to humidify the respiration air A61M16/1045 takes precedence
• CPC Class Codes: A61M 16/201 : Controlled valves
• CPC Class Codes: A61M 16/208 : Non-controlled one-way valves, e.g. exhalation, check, pop-off non-rebreathing valves
• CPC Class Codes: A61M 2016/0015 : inhalation detectors
• CPC Class Codes: A61M 2016/0021 : with a proportional output signal, e.g. from a thermistor
• CPC Class Codes: A61M 2016/0024 : with an on-off output signal, e.g. from a switch
• CPC Class Codes: A61M 2016/0027 : pressure meter
• CPC Class Codes: A61M 2016/0036 : in the breathing tube and used in both inspiratory and expiratory phase
• CPC Class Codes: A61M 2016/0661 : with customised shape
• CPC Class Codes: A61M 2202/0007 : introduced into the body
• CPC Class Codes: A61M 2202/0208 : Oxygen
• CPC Class Codes: A61M 2202/03 : Gases in liquid phase, e.g. cryogenic liquids
• CPC Class Codes: A61M 2205/0205 : Materials having antiseptic or antimicrobial properties, e.g. silver compounds, rubber with sterilising agent
• CPC Class Codes: A61M 2205/17 : with redundant control systems
• CPC Class Codes: A61M 2205/3334 : Measuring or controlling the flow rate
• CPC Class Codes: A61M 2205/8206 : battery-operated
• CPC Class Codes: A61M 2230/40 : Respiratory characteristics

Abstract

A system for reducing airway obstructions of a patient may include a ventilator, a control unit, a gas delivery circuit with a proximal end in fluid communication with the ventilator and a distal end in fluid communication with a nasal interface, and a nasal interface. The nasal interface may include at least one jet nozzle, and at least one spontaneous respiration sensor in communication with the control unit for detecting a respiration effort pattern and a need for supporting airway patency. The system may be open to ambient. The control unit may determine more than one gas output velocities. The more than one gas output velocities may be synchronized with different parts of a spontaneous breath effort cycle, and a gas output velocity may be determined by a need for supporting airway patency.

Claims

1-56. -56. (canceled)

57. A system for reducing airway obstructions of a patient, the system comprising:

a ventilator;

a control unit; and

a gas delivery circuit with a proximal end in fluid communication with the ventilator and a distal end in fluid communication with a nasal interface;

the nasal interface comprising;

at least one outer tube having including a support therein, the outer tube and support at least partially defining a primary gas flow path;

at least one jet nozzle extending at least partially through the support and defining a gas delivery path in fluid communication with the primary gas flow path;

at least one entrainment aperture disposed in the support and defining an ambient air delivery path in fluid communication with ambient air, wherein the at least one entrainment aperture is oriented relative to the at least one jet nozzle such that an air delivery path axis defined by the ambient air delivery path extends in generally parallel relation to a gas delivery path axis defined by the gas delivery path; and

at least one spontaneous respiration sensor in communication with the control unit for detecting a respiration effort pattern and a need for supporting airway patency,

wherein the control unit determines a plurality of baseline gas output velocities which are synchronized with different parts of a spontaneous breath effort cycle, and adjusts the plurality of baseline gas output velocities as determined by the need for supporting airway patency.

58. The system of claim 57, wherein the at least one entrainment aperture comprises a plurality at entrainment apertures which are arranged in a generally circular pattern at least partially circumventing the at least one jet nozzle such that the air delivery path axis defined by the ambient air delivery path of each of the entrainment apertures extends in generally parallel relation to the gas delivery path axis defined by the gas delivery path of the jet nozzle.

59. The system of claim 57, wherein the at least one entrainment aperture comprises an arcuate channel at least partially circumventing the at least one jet nozzle such that the air delivery path axis defined by the ambient air delivery path of the channel extends in generally parallel relation to the gas delivery path axis defined by the gas delivery path of the jet nozzle.

60. The system of claim 57, wherein the nasal interface further comprises a secondary gas flow path which is oriented relative to the primary gas flow path such that the primary and secondary gas flow paths are coaxially aligned with each other, with the secondary gas flow path at least partially circumventing the primary gas flow path.

61. The system of claim 60, wherein the outer tube has a generally circular cross-sectional configuration, and the secondary gas flow path is collectively defined by the outer tube and an inner tube which has a generally circular cross-sectional configuration and is concentrically positioned within the outer tube.

62. The system of claim 61, wherein the primary gas flow path defines a primary gas flow path axis, and the gas delivery path axis defined by the gas delivery path of the jet nozzle is coaxially aligned with the primary gas flow path axis.

63. The system of claim 57, wherein the primary gas flow path defines a primary gas flow path axis and the gas delivery path axis defined by the gas delivery path of the jet nozzle is angled with respect to primary gas flow path axis such that pressurized gas delivered by the at least one jet nozzle into the primary gas flow path is directed away from the primary gas flow path axis toward the outer tube.

64. The system of claim 57, wherein the nasal interface further includes:

at least one coupler at a distal section of the at least one outer tube for impinging at least one nostril and positioning the at least one outer tube relative to the at least one nostril; and

at least one opening in the distal section adapted to be in fluid communication with the nostril;

wherein the at least one jet nozzle is in fluid communication with a pressurized gas supply.

65. The system of claim 64, wherein the at least one coupler is a nasal cushion.

66. The system of claim 57, further comprising a portable ventilation gas supply, and wherein the ventilator is portable.

67. The system of claim 57, wherein the control unit adjusts an output of the ventilator to match a patient'"'"'s needs based on information from the at least one spontaneous respiration sensor.

68. A system for reducing airway obstructions of a patient, the system comprising:

a ventilator; and

a nasal interface in fluid communication with the ventilator, and comprising;

at least one outer tube having including a support therein, the outer tube and support at least partially defining a primary gas flow path;

at least one jet nozzle extending at least partially through the support and defining a gas delivery path in fluid communication with the primary gas flow path; and

at least one entrainment aperture disposed in the support and defining an ambient air delivery path in fluid communication with ambient air, wherein the at least one entrainment aperture is oriented relative to the at least one jet nozzle such that an air delivery path axis defined by the ambient air delivery path extends in generally parallel relation to a gas delivery path axis defined by the gas delivery path.

69. The system of claim 68, wherein the at least one entrainment aperture comprises a plurality at entrainment apertures which are arranged in a generally circular pattern at least partially circumventing the at least one jet nozzle such that the air delivery path axis defined by the ambient air delivery path of each of the entrainment apertures extends in generally parallel relation to the gas delivery path axis defined by the gas delivery path of the jet nozzle.

70. The system of claim 68, wherein the at least one entrainment aperture comprises an arcuate channel at least partially circumventing the at least one jet nozzle such that the air delivery path axis defined by the ambient air delivery path of the channel extends in generally parallel relation to the gas delivery path axis defined by the gas delivery path of the jet nozzle.

71. The system of claim 68, wherein the nasal interface further comprises a secondary gas flow path which is oriented relative to the primary gas flow path such that the primary and secondary gas flow paths are coaxially aligned with each other, with the secondary gas flow path at least partially circumventing the primary gas flow path.

72. The system of claim 71, wherein the outer tube has a generally circular cross-sectional configuration, and the secondary gas flow path is collectively defined by the outer tube and an inner tube which has a generally circular cross-sectional configuration and is concentrically positioned within the outer tube.

73. The system of claim 72, wherein the primary gas flow path defines a primary gas flow path axis, and the gas delivery path axis defined by the gas delivery path of the jet nozzle is coaxially aligned with the primary gas flow path axis.

74. The system of claim 68, wherein the primary gas flow path defines a primary gas flow path axis and the gas delivery path axis defined by the gas delivery path of the jet nozzle is angled with respect to primary gas flow path axis such that pressurized gas delivered by the at least one jet nozzle into the primary gas flow path is directed away from the primary gas flow path axis toward the outer tube.

75. The system of claim 68, wherein the nasal interface further includes:

at least one coupler at a distal section of the at least one outer tube for impinging at least one nostril and positioning the at least one outer tube relative to the at least one nostril; and

at least one opening in the distal section adapted to be in fluid communication with the nostril;

wherein the at least one jet nozzle is in fluid communication with a pressurized gas supply.

76. The system of claim 75, wherein the at least one coupler is a nasal cushion.