BIOSYNTHETIC IMPLANT FOR SOFT TISSUE REPAIR
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Abstract
An implant and a process for preparing such an implant are disclosed. The implant includes a porous layer including collagen, a non-porous layer including a collagenic constituent, and a reinforcement component. The non-porous layer is joined to the porous layer and the reinforcement member is embedded into the non-porous layer. The porous layer has a three dimensional density ranging from about 20 mg collagen/cm3 to about 200 mg collagen/cm3.
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Citations
39 Claims
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1-17. -17. (canceled)
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18. A process for preparing an implant having a porous layer, a non-porous layer and a reinforcement member comprising:
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preparing a composition comprising collagen, using purified fibers of collagen as starting material; freeze drying the prepared composition to obtain a porous layer, compressing the porous layer to obtain a three dimensional density ranging from about 20 mg collagen/cm3 to about 200 mg collagen/cm3; pouring a solution of a collagenic constituent onto a support to obtain a non-porous layer; applying a reinforcement member on a top surface of the non-porous layer, and applying the compressed porous layer on the top surface of the non-porous layer, during gelification of the non-porous layer. - View Dependent Claims (19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38)
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39. A process for preparing an implant having a porous layer, a non-porous layer and a reinforcement member comprising:
- freeze drying a composition comprising collagen to obtain a porous layer, compressing the porous layer to obtain a three dimensional density ranging from about 20 mg collagen/cm3 to about 200 mg collagen/cm3;
pouring a solution of a collagenic constituent onto a support to obtain a non-porous layer;
applying a reinforcement member on a top surface of the non-porous layer, and applying the compressed porous layer on the top surface of the non-porous layer, during gelification of the non-porous layer.
- freeze drying a composition comprising collagen to obtain a porous layer, compressing the porous layer to obtain a three dimensional density ranging from about 20 mg collagen/cm3 to about 200 mg collagen/cm3;
Specification