QUINAZOLINONES AND AZAQUINAZOLINONES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS
6 Assignments
0 Petitions
Accused Products
Abstract
The present disclosure relates to inhibitors of USP7 inhibitors useful in the treatment of cancers, neurodegenerative diseases, immunological disorders, inflammatory disorders, cardiovascular diseases, ischemic diseases, viral infections and diseases, and bacterial infections and diseases, having the Formula:
where R1, R2, R3, R4, R4′, X1, Y1, Y2, Y3, Y4, n, and m are described herein.
26 Citations
46 Claims
- 1. A compound of Formula (I):
-
12-13. -13. (canceled)
-
15. (canceled)
-
17. (canceled)
-
23. (canceled)
-
26. (canceled)
-
28. (canceled)
-
33-34. -34. (canceled)
-
36. (canceled)
-
38. (canceled)
-
41-44. -44. (canceled)
-
46-47. -47. (canceled)
Specification