COMPLIANT COUPLING ASSEMBLY FOR CARTRIDGE COUPLING OF A DRUG DELIVERY DEVICE

• US 20160256352A1
• Filed: 03/04/2015
• Published: 09/08/2016
• Est. Priority Date: 03/04/2015
• Status: Active Grant

• Current Assignee: West Pharma. Services IL, Ltd. (West Pharmaceutical Services Incorporated)
• Original Assignee: Medimop Medical Projects Ltd. (West Pharmaceutical Services Incorporated)
• Inventors: VENISLAVSKI, Evgeni, BAR-EL, Yossi, SOLOMON, Tomer, FILMAN, Reuven Y.
• Granted Patent: US 9,795,534 B2
• Time in Patent Office: Days
• US Class Current: 1/1
• CPC Class Codes: A61J 1/1406 Septums, pierceable membranes
• CPC Class Codes: A61M 2005/341 angularly adjustable or angled away from the axis of the injector
• CPC Class Codes: A61M 2209/045 for filling, e.g. for filling reservoirs
• CPC Class Codes: A61M 5/1413 Modular systems comprising interconnecting elements
• CPC Class Codes: A61M 5/1456 with a replaceable reservoir comprising a piston rod to be moved into the reservoir, e.g. the piston rod is part of the removable reservoir
• CPC Class Codes: A61M 5/162 Needle sets, i.e. connections by puncture between reservoir and tube ; Connections between reservoir and tube in jet-action syringes A61M5/30; connectors for tubes having sealed ends and a needle for piercing them A61M39/14
• CPC Class Codes: A61M 5/1782 Devices aiding filling of syringes in situ combination of a vial and a syringe for transferring or mixing their contents A61J1/2096, filling of medical containers in general B65B3/003

Abstract

An assembly for coupling a drug delivery device to a cartridge is disclosed. Optionally the assembly includes a coupling, for example a cannula, having one end extending toward the cartridge. The cartridge is optionally aligned by a guide. Optionally the cartridge has a limited freedom of movement. The coupling is optionally supported by a mount. In some embodiments, the mount is compliant enough that the end of the coupling that extends toward may move to said limited freedom of movement under a force less than a leak threshold of the connection between the coupler and the cartridge.

Claims

1. An assembly for coupling a drug delivery device to a cartridge sealed by a septum having a leak threshold force, the apparatus comprising:

a cannula having a tip region configured to penetrate the septum, said tip region having a width;

a frame including;

a guide sized and shaped to secure the cartridge to said frame; and

a mount attached to said cannula;

said mount positioned on said frame so that said tip region of said cannula protrudes through the septum of the cartridge when said cartridge is secured to said frame by said guide;

said mount is compliant enough so that a force of less than a leak threshold force of said septum moves said tip region of said cannula transaxially at least distance equal to said width.

2. The assembly of claim 1, wherein said mount is compliant enough so that a force of less than a leak threshold force of said septum moves said tip region of said cannula transaxially at least distance equal to a position deviation tolerance of said septum.

3. The assembly of claim 1, wherein said distance is greater than a movement caused by a flexibility of said frame and said cannula under said leak threshold force.

4. The assembly of claim 1, wherein said mount compensates for a movement of said cannula at a stress level less than a stress then a bending stress of said cannula.

5. The assembly of claim 1, wherein said leak threshold force is 6 N.

6. The assembly of claim 1, further comprising:

a base located on a side of said cannula opposite said tip region, said base inhibiting backwards movement of said tip region.

7. The assembly of claim 6, wherein said base is positioned off axis of said cannula.

8. The assembly of claim 1, wherein said mount is configured to bias movement of said cannula is a particular direction.

9. The assembly of claim 8, wherein said particular direction is parallel to a face of a bevel of a tip of said cannula.

10. The assembly of claim 1, wherein said cannula is bent at an angle ranging between 30 to 80 degrees.

11. The assembly of claim 1, further comprising:

a second end of said cannula connected to a flexible fluid path.

12. The assembly of claim 1, further including:

the cartridge is coupleable to said cannula by a linear movement of the cartridge with respect to the guide.

13. The assembly of claim 1, wherein said compliant mount is flexible.

14. A method of supplying a drug to a delivery device comprising:

loading a cartridge containing the drug into the delivery device;

piercing a septum with a cannula;

opening a flow path between said cannula and an internal fluid path of the drug delivery device;

limiting transaxial movement of said septum to less than a first deviation tolerance; and

allow transverse movement of a septum interface region of said cannula to adjust to said movement.

15. The method of claim 14, wherein said transaxial movements of the cannula are caused by a stress less than a leak threshold of the septum.

16. The method of claim 14, wherein said allowing movement is in one direction more than another direction.

17. The method of claim 16, wherein said more movement is allowed in the direction opposite a face of a bevel of said cannula than in a direction of said face of a bevel of said cannula.

18. The method of claim 16, wherein said more movement is allowed parallel to a direction faced by a bevel of said cannula than in a direction perpendicular thereto.

19. The method of claim 14, wherein said allowing movement is less when there is an axial stress against a tip of said cannula than when said cannula not under axial stress.

20. The method of claim 14, where said allowing movement is elastic.